Risk factors associated with prevalent and incident syphilis among an HIV-infected cohort in Northeast China

Hu, Qing-hai; Xu, Jun-jie; Zou, Hua-chun; Liu, Jing; Zhang, Jing; Ding, Hai-bo; Qian, Han-Zhu; Li, Si-ruo; Liu, Yu; Jiang, Yong-jun; Shang, Hong; Wang, Ning

doi:10.1186/s12879-014-0658-1

BMC Infectious Diseases

Table 1 Characteristics of PLWHA with prevalent and incident syphilis in Shenyang

From: Risk factors associated with prevalent and incident syphilis among an HIV-infected cohort in Northeast China

Characteristic	Syphilis infection at baseline			Syphilis seroconversion during follow-up
Characteristic	No. of participants	Seropositive cases	Prevalence (%)	No. of participants	Person–years (PY)	Incident cases	Incidence (per 100 PY)
Overall	1010	200	19.8	634	702.3	131	18.7
Gender
Female	68	4	5.9	51	40.6	3	7.4
Male	942	196	20.8	583	661.8	128	19.3
Age (year)
Median(IQR)	35(27-46)			35(27-46)
≤24	142	22	15.5	92	124.8	8	6.4
25-39	461	77	16.7	299	353.7	43	12.2
≥40	407	101	24.8	243	223.9	80	35.7
Ethnicity
Han	883	182	20.6	552	607.0	115	19.0
Other ethnicities	127	18	14.2	82	95.3	16	16.8
Marital status
Single	522	102	19.5	317	376.0	54	14.4
Married	330	62	18.8	213	219.3	44	20.1
Divorced	158	36	22.8	104	107.1	33	30.8
Occupation
Employed	645	129	20.0	415	461.3	90	19.5
Unemployed	198	36	18.2	123	120.0	24	20.0
Retired	76	22	29.0	43	46.5	14	30.1
Student	91	13	14.3	53	74.7	3	4.0
Education
Less than high school	351	77	21.9	209	225.4	46	20.4
High school or more	659	123	18.7	425	476.9	85	17.8
Shenyang resident
Yes	885	181	20.5	560	601.4	115	19.1
No	125	19	15.2	74	100.9	16	15.9
HIV transmission route
Heterosexual	146	16	11.0	103	88.2	15	17.0
MSM	778	171	22.0	478	570.0	111	19.5
Others (injection drug use, blood, unknown)	86	13	15.1	53	44.2	5	11.3
HIV diagnosis venue
VCT	277	54	19.5	182	244.9	41	16.7
Hospital	366	87	23.8	242	281.3	59	21.0
Others (blood donation, physical exam, etc.)	57	6	10.5	48	70.0	5	7.2
Unknown	310	53	17.1	162	106.2	26	24.5
ART at baseline
No	687	159	23.1	385	501.0	68	13.6
Yes	323	41	12.7	249	201.3	63	31.3
Time since HIV diagnosis (year)
≤2	730	156	21.4	439	514.1	79	15.4
>2	280	44	15.7	195	188.2	52	27.6
Baseline CD ₄ ⁺ T cell counts(counts/mm ³ )
≥500	152	28	18.4	95	126.3	20	21.1
350-499	255	40	15.7	173	194.1	41	23.7
200-349	331	62	18.7	214	226.7	36	16.8
<200	246	65	26.4	142	137.7	30	21.1
Unknown	26	5	19.2	10	17.5	4	40.0
Baseline VL (copies/mL)
≤100,000	599	118	19.7	378	455.6	77	16.9
>100,000	148	46	31.1	72	85.5	13	15.2
Unknown	263	36	13.7	184	161.2	41	25.4

IQR: interquartile range; VCT: voluntary counseling and testing; ART: antiretroviral therapy; VL: viral load; PY: person year.

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ISSN: 1471-2334

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