Characteristic at time of first positive NTM culture | LAM positive ( n = 9) | LAM negative ( n = 14) | p -value |
---|---|---|---|
Median age (IQR), y | 19.7 (13.7 – 25.6) | 16.1 (11.9 – 24.0) | 0.41 |
Female, % | 88.9 | 28.6 | 0.01 |
Homozygote for Delta 508, % | 78.8 | 85.7 | 0.62 |
Median FEV1% of pred. (IQR) | 80.0 (70.3 – 84.8) | 70.0 (66.3 – 83.5) | 0.59 |
Diabetes mellitus, % | 11.1 | 28.6 | 0.32 |
Structurally defective MBL allele*, % | 55.6 | 7.1 | 0.01 |
Other chronic infection, % | 77.8 | 50.0 | 0.18 |
Received NTM treatment, % | 55.6 | 57.1 | 0.94 |
Number of positive NTM cultures | 11.0 (3.5 – 19.5) | 6.0 (1.8 – 14.5) | 0.68 |
MABSC, % | 88.9 | 64.3 | 0.19 |
Fulfilled ATS criteria for NTM, % | 88.9 | 78.6 | 0.52 |
Median time positive for NTM (IQR), y | 2.5 (1.0 – 4.0) | 3.0 (1.0 – 5.0) | 1.00 |
Chronic renal disease**, % | 0 | 14.3 | 0.24 |