Clinical and treatment-related risk factors for nosocomial colonisation with extensively drug-resistant Pseudomonas aeruginosa in a haematological patient population: a matched case control study

Table 2 Multivariate analysis (Step III): Odds ratios for risk of XDR-PA colonisation

Variable	OR (95% CI)	P-value
Clinical parameters*
Central venous catheter	7.41 (1.98 - 27.68)	0.0008
Urinary catheter	21.04 (3.67 - 120.57)	<0.0001
CRP > 10 mg/dl	7.36 (1.81 - 29.85)	0.0015
Treatment parameters – drug
Ciprofloxacin use	5.53 (1.11 - 27.53)	0.025
Ceftazidime use	1.9 (0.22 - 16.43)	0.56
NDA > 3	2.22 (0.36 - 13.65)	0.39
Treatment parameters – length of treatment
Ciprofloxacin, antibiotic-days	1.01 (0.88 - 1.16)^‡	0.88
Treatment parameters – total dosage
Ciprofloxacin total dose, DDD	1.01 (0.87 - 1.17)^‡	0.91

*The results shown are based on the final model with the treatment-related variables for use of antibiotics.
^‡Per 1 unit increase.
XDR-PA, extensively drug-resistant Pseudomonas aeruginosa; CRP, C-reactive protein; NDA, number of different antibiotics during time at risk; DDD, defined daily dose; 95% CI, 95% confidence interval.

ISSN: 1471-2334