Table 3 Significantly associated clinical and laboratory variables at first presentation of dengue-infected ICU (cases) compared to non-ICU (controls) patients

Hypoproteinemia

Yes

23

21

10

37

2.28

0.085

0.89–5.85

4.65

0.037

1.09–19.74

Hypotension

Yes

4

3.7

7

26

8.62

0.002

2.21–33.63

7.63

0.005

1.83–31.79

Severe organ involvement

Yes

1

0.9

10

37

40

<0.001

5.12–312.5

33.04

0.003

3.30–331.3

Hematocrit change ≥20% concurrent with platelet <50 K

Yes

7

6.5

11

41

9.4

<0.001

2.95–29.83

8.66

0.001

2.46–30.53

Systolic blood pressure

105

(100–114)

110

(91.5–118.5)

0.98

0.216

0.96–1.01

0.97

0.046

0.94–0.99

Pulse rate

90

(80–96)

95.5

(88.5–102)

1.03

0.049

1.00–1.07

1.05

0.012

1.01–1.09

Proportion neutrophils

60.3

(46.2–70.4)

76.8

(70.7–81.5)

1.11

<0.001

1.05–1.18

1.11

0.001

1.04–1.17

Proportion lymphocytes

30.3

(22–39)

16.5

(9.8–19.9)

0.90

<0.001

0.85–0.95

0.90

0.001

0.85–0.96

Proportion monocytes

12.5

(8.9–17.3)

7.9

(5.1–9.9)

0.84

0.002

0.76–0.94

0.86

0.004

0.77–0.95

Platelet

68

(44–84)

42.5

(20.3–74.8)

0.98

0.01

0.96–0.99

0.98

0.017

0.96–0.99

Serum urea

3.5

(2.6–4.6)

5.1

(3.7–6.8)

1.33

0.002

1.11–1.58

1.26

0.030

1.02–1.56

Serum creatinine

77

(65–88.3)

102

(82.3–130)

1.03

0.001

1.01–1.04

1.02

0.006

1.01–1.04

Serum AST

114

(70–195)

156.5

(96.5–516)

1.01

0.017

1.00–1.04

1.01

0.019

1.00–1.04

Serum ALT

74

(38–121)

92

(55.8–293.3)

1.01

0.012

1.001–1.06

1.01

0.017

1.001–1.06

Serum protein

67

(63–72)

66

(60.5–68.5)

0.89

0.016

0.79–0.98

0.88

0.022

0.79–0.98

Serum albumin

37

(35–40)

37

(31–39)

0.8

0.004

0.69–0.93

0.81

0.006

0.70–0.94