Skip to main content

Table 2 Severity classification and duration of illness of dengue-infected non-ICU (controls) and ICU (cases) patients

From: Early clinical and laboratory risk factors of intensive care unit requirement during 2004–2008 dengue epidemics in Singapore: a matched case–control study

Variables

Den-infected non-ICU controls (n = 108)

%/(IQR)

Den-infected ICU cases (n = 27)

%/(IQR)

COR

P-value

95% CI

ACOR*

P-value

95% CI

WHO 1997 (Presentation)

          

DHF/DSS

14

13

5

19

1.5

0.469

0.50–4.4

1.8

0.34

0.54–6.08

WHO 2009 (Presentation)

          

Severe dengue

7

6.5

14

52

10.3

<0.001

3.70–28.84

8.79

<0.001

2.65–29.16

WHO 1997 (Outcome)

          

DHF/DSS

24

22

18

67

7.65

<0.001

2.74–21.35

2.99

0.025

1.15–7.78

WHO 2009 (Outcome)

          

Severe dengue

11

10

24

89

73.1

<0.001

9.82–543.96

116.4

<0.001

8.79–1541

Median DPP to DHF/DSS

3

(2.3–3.8)

4

(3–5)

1.79

0.206

0.73–4.43

3.08

0.677

0.02–608

Median DPP to Severe dengue

2.5

(1.8–3.3)

3

(3–5)

      

Median LOS in hospital

4

(3–5)

8

(6–13.5)

1.73

<0.001

1.30–2.32

1.76

0.001

1.28–2.43

Median DPF on ICU requirement

N.A

 

6

(4–7.5)

      

Median DPP on ICU requirement

N.A

 

3

(2–4.5)

      

Median LOS in ICU

N.A

 

3

(2–4)

      

Death

0

0

7

26

      

Median DPF to death

N.A

 

7

(7–15.5)

      

Median DPP to Death

N.A

 

3

(2.5–7.5)

      
  1. DPF- Days Post Fever; DPP- Days Post Presentation; LOS- Length of Stay; COR- Conditional Odds Ratio; IQR- Interquartile range.
  2. *Adjusted Conditional Odds Ratio (ACOR) was obtained from a multivariate conditional logistic regression with test variables being adjusted by age and diabetes mellitus.
  3. Data in bold are risk factors significantly associated with ICU requirement.