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Figure 3 | BMC Infectious Diseases

Figure 3

From: Analysis of nucleotide-binding oligomerization domain proteins in a murine model of pneumococcal meningitis

Figure 3

The activation of NF-kB is increased following infection with S. pneumoniae (A). Vehicle (0) or S. pneumoniae (1 × 106 bacteria) was administered to the rats via intracisternal injection. At days 1 (D1), D2, and D3 postinfection, the brain tissue was isolated, and the nuclear protein was prepared for immunoblot assays of the presence of NF-kB p65 (Panel A). The bands were quantified by densitometric analyses and normalized to β-actin expression (Panel B). The asterisks indicate statistically significant differences compared to the uninfected animals (p < 0.05).

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