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Table 4 Helminth infections and significantly associated factors according to stepwise backwards multivariable regression analyses in infants, preschool-aged (PSAC), and school-aged children (SAC) from the Bagamoyo district, United Republic of Tanzania

From: Enterobiasis and strongyloidiasis and associated co-infections and morbidity markers in infants, preschool- and school-aged children from rural coastal Tanzania: a cross-sectional study

Helminth infection

Age-group

Explanatory variable

n

OR

95% Confidence interval

p- value

Original model run with*

E . vermicularis

all age-groups

Gender

585

0.70

(0.45 - 1.11)

0.127

9,1,2,3,4,6,7,16,17,20

  

Age (month)

 

1.03

(1.02 - 1.05)

<0.001

 
  

Temperature

 

1.60

(0.96 - 2.67)

0.071

 
  

Weight

 

0.91

(0.82 - 1.00)

0.051

 
  

Anthelmintic treatment

 

2.15

(1.22 - 3.79)

0.008

 
  

Neutrophil counts

 

1.10

(1.01 - 1.20)

0.034

 
 

Infants

Gender

158

3.72

(0.68 - 20.36)

0.129

9,1,2,3,21

  

Age (month)

 

1.13

(1.01 - 1.27)

0.027

 
 

PSAC

Gender

201

0.51

(0.23 - 1.16)

0.108

9,1,2,3,16

  

Anthelmintic treatment

 

3.60

(1.01 - 12.86)

0.049

 
  

Neutrophil counts

 

1.09

(1.00 - 1.19)

0.041

 
 

SAC

Temperature

315

2.21

(1.13 - 4.33)

0.021

9,1,2,3,4

  

Anthelmintic treatment

 

1.78

(0.94 - 3.36)

0.076

 

S . stercoralis

all age-groups

Gender

624

0.62

(0.32-1.21)

0.163

11,1,2,3,4,10,12,13,14,19

  

Anthelmintic treatment

 

1.65

(0.80-3.41)

0.178

 
  

T. trichiura

 

4.13

(1.04-16.52)

0.045

 
  

Asymptomatic Plasmodium parasitaemia

2.10

(0.97-4.51)

0.058

 
  

Eosinophil counts

 

2.04

(1.20-3.48)

0.008

 
  

Platelet counts

 

1.00

(0.99-1.00)

0.064

 
 

Infants

Gender

132

0.13

(0.01 - 1.38)

0.091

11,1,2,3,6,7,13,14

  

Age (month)

 

1.20

(0.97 - 1.49)

0.086

 
  

Asymptomatic Plasmodium parasitaemia

13.03

(1.34 - 127.23)

0.027

 
  

Eosinophil counts

 

4.00

(1.10 - 14.58)

0.036

 
 

PSAC

Light anaemia

303

0.19

(0.04 - 0.82)

0.026

11,1,2,3,21

 

SAC

T. trichiura

290

3.59

(0.80 - 16.08)

0.095

11,1,2,3,4,12,14,19

  

Eosinophil counts

 

2.15

(1.10 - 4.23)

0.026

 
  

Platelet counts

 

0.99

(0.98 - 1.00)

0.011

 

Hookworm

all age-groups

Temperature

623

1.77

(0.83 - 3.78)

0.143

10,1,2,3,4,6,7,11,12,14,16,20

  

Weight

 

1.12

(1.05 - 1.18)

<0.001

 
  

T. trichiura

 

3.33

(0.77 - 14.39)

0.107

 
  

Eosinophil counts

 

2.30

(1.29 - 4.09)

0.005

 
 

Infants

Anthelmintic treatment

138

27.91

(5.52 - 141.21)

<0.001

10,1,2,3,6,7,14,16,20

  

Eosinophil counts

 

16.60

(1.39 - 198.32)

0.026

 
  

Basophil counts

 

0.10

(0.01 - 0.86)

0.036

 
  

Haemoglobin

 

1.96

(1.13 - 3.41)

0.016

 
 

PSAC

Gender

272

1.97

(0.72 - 5.38)

0.185

10,1,2,3,4,12,16

  

Temperature

 

3.74

(1.14 - 12.28)

0.030

 
  

Anthelmintic treatment

 

0.52

(0.2 - 1.34)

0.174

 
  

T. trichiura

 

22.78

(4.43 - 117.23)

<0.001

 
  

Neutrophil counts

 

1.11

(1.01 - 1.21)

0.03

 
 

SAC

Eosinophil counts

295

2.71

(1.39 - 5.31)

0.004

10,1,2,3,14,27

T . trichiura

all age-groups

Anthelmintic treatment

623

0.12

(0.03 - 0.54)

0.005

12,1,2,3,11,14,18

  

S. stercoralis

 

5.18

(1.45 - 18.46)

0.011

 
  

Eosinophil counts

 

3.28

(1.69 - 6.36)

0.001

 
  

Monocyte counts

 

0.02

(0.00 - 0.33)

0.007

 
 

Infants

Age (month)

55

0.51

(0.31 - 0.85)

0.009

12,1,2,3

 

PSAC

Hookworm

297

11.53

(2.30 - 57.77)

0.003

12,1,2,3,10,19

  

Platelet counts

 

1.01

(1.00 - 1.01)

0.008

 
 

SAC

Anthelmintic treatment

290

0.08

(0.01 - 0.48)

0.006

12,1,2,3,6,11,14

  

S. stercoralis

 

6.63

(1.52 - 28.93)

0.012

 
  

Eosinophil counts

 

3.23

(1.73 - 6.02)

0.001

 

Plasmodium parasitaemia

all age-groups

Age (month)

952

1.03

(1.02 - 1.04)

<0.001

13,1,2,3,6,7,19,20

  

Anthelmintic treatment

 

0.73

(0.49 - 1.10)

0.137

 
  

Haemoglobin

 

0.65

(0.56 - 0.76)

<0.001

 
  

Platelet counts

 

1.00

(0.99 - 1.00)

0.012

 
 

Infants

Gender

177

2.88

(0.79 - 10.55)

0.111

13,1,2,3,6,7,11,19

  

Weight

 

1.39

(0.97 - 1.99)

0.071

 
  

S. stercoralis

 

5.75

(1.21 - 27.41)

0.028

 
  

Platelet counts

 

0.99

(0.99 - 1.00)

0.022

 
 

PSAC

Weight

230

1.27

(1.06 - 1.52)

0.010

13,1,2,3,7,18,20

  

Haemoglobin

 

0.49

(0.34 - 0.73)

<0.001

 
  

Monocyte counts

 

13.88

(3.42 - 56.30)

<0.001

 
 

SAC

Age (month)

312

1.03

(1.01 - 1.05)

0.004

13,1,2,3,18,20

  

Anthelmintic treatment

 

0.65

(0.36 - 1.19)

0.161

 
  

Haemoglobin

 

0.69

(0.53 - 0.90)

0.007

 
  

Monocyte counts

 

2.54

(0.77 - 8.37)

0.126

 

Plasmodium parasitaemia

<2 years

Light anaemia

625

1.84

(1.04 - 3.27)

0.037

13,1,2,3,21

  

Moderate anaemia

 

5.36

(2.92 - 9.82)

<0.001

 
  

Severe anaemia

 

11.20

(4.20 - 29.86)

<0.001

 
  

Age (month)

 

1.04

(1.025 - 1.05)

<0.001

 
  

Anthelmintic treatment

 

0.72

(0.47 - 1.10)

0.129

 
 

>2 years

Light anaemia

537

1.57

(0.88 - 2.78)

0.123

13,1,2,3,21

  

Moderate anaemia

 

3.07

(1.96 - 4.81)

<0.001

 
  

Severe anaemia

 

7.27

(2.04 - 25.96)

0.002

 
  

Gender

 

0.70

(0.47 - 1.04)

0.076

 
  

Age (month)

 

1.02

(1.00 - 1.03)

0.021

 
  1. *Explanatory variables with significant outcome in the univariable analysis and included in the original model of the multivariate analysis 1: Gender; 2: Age (month); 3: Anthelmintic treatment; 4: Temperature; 5: mid-upper arm circumference (MUAC); 6: Height; 7: Weight; 8: A. lumbricoides infection; 9: E. vermicularis infection; 10: Hookworm infection; 11: S. stercoralis infection; 12: T. trichiura infection; 13: Asymptomatic Plasmodium parasitaemia; 14: Eosinophil counts; 15: Basophil counts; 16: Neutrophil counts; 17: Lymphocyte counts; 18: Monocyte counts; 19: Platelet counts; 20: Haemoglobin; 21: Anaemia; 22: Malnutrition; 23: Stunting; 24: Thinness; 25: Underweight; 26: Wasting; 27: Fever.
  2. The table shows the significant explanatory variables that remained in the final model with p < 0.2.