Table 3 DEPDC5 genetic variations between chronic HCV-infected patients and control group

rs1012068

GG

64 (10.8%)

33 (5.5%)

0.414 (0.264-0.651)

15.200

<0.0001

GT

278 (47%)

257 (42.8%)

0.743 (0.586-0.943)

6.010

0.014

TT

250 (42.2%)

311 (51.7%)

Ref

GG + GT.VS.TT

0.682 (0.542-0.857)

10.840

<0.001

TT + GT.VS.GG

2.086 (1.348-3.228)

11.300

0.0008

Allele

G

406 (34.3%)

323 (26.9%)

0.704 (0.591-0.839)

15.470

<0.0001

T

778 (65.7%)

879 (73.1%)

rs5998152

CC

60 (10%)

39 (6.5%)

0.544 (0.352-0.840)

7.670

0.006

CT

271 (46%)

250 (41.6%)

0.772 (0.608-0.979)

4.570

0.033

TT

261 (44%)

312 (51.9%)

Ref

CC + CT.VS.TT

0.730 (0.582-0.917)

7.320

0.007

TT + CT.VS.CC

1.625 (1.068-2.474)

5.210

0.022

Allele

C

391 (33%)

328 (27.3%)

0.761 (0.639-0.907)

9.320

0.002

T

793 (67%)

874 (72.7%)