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Table 8 Microbiological success (eradication of bacteriuria) in the different evaluation sets

From: Review of the literature and individual patients’ data meta-analysis on efficacy and tolerance of nitroxoline in the treatment of uncomplicated urinary tract infections

Evaluation set Nitroxoline Controls Difference (%) (95%-CI) Odds ratio (95%-CI)
mMITT 192/211 (91.0%) 203/213 (95.3%) −3.4 (−9.7 to 3.0) 0.47 (0.21 to 1.06)
PP 184/200 (92.0%) 197/206 (95.6%) −2.2 (−8.2 to 3.7) 0.47 (0.19 to 1.14)
mPP 185/205 (90.2%) 197/210 (93.8%) −2.9 (−9.9 to 4.1) 0.60 (0.28 to 1.27)
  1. mMITT-modified microbiological intention to treat; PP-per protocol; mPP-modified per protocol.
  2. Difference: nitroxoline – controls.
  3. Odds Ratio: nitroxoline vs controls.
  4. Estimation by logistic regression with random center effect.