Skip to main content

Advertisement

Table 1 In vitro antimicrobial susceptibility of Neisseria gonorrhoeae : clinical isolates (n = 334)

From: Antimicrobial susceptibility of Neisseria gonorrhoeaeisolates from symptomatic men attending the Nanjing sexually transmitted diseases clinic (2011–2012): genetic characteristics of isolates with reduced sensitivity to ceftriaxone

Antimicrobial breakpoints (susceptible/resistant [mg/L]) a No. (%) MIC (mg/L)
Susceptible Intermediate Resistant Range MIC 50 MIC 90
Penicillin G (S ≤ 0.06/R ≥ 2) 0 108 (32.3) 226 (67.7) 0.125 to >8 2 >8
Tetracycline (S ≤ 0.25/R ≥ 2) 2 (0.6) 5 (1.5) 327 (97.9) 0.25 to >16 8 >16
Ciprofloxacin (S ≤ 0.06/R ≥ 1) 0 4 (1.2) 330 (98.8) ≤0.25 to >8 >8 >8
Spectinomycin (S ≤ 32/R ≥ 128) 334 (100) 0 0 ≤4 to 32 16 32
Ceftriaxone (S ≤ 0.25) 334 (100) - - 0.004 to 0.25 0.03 0.06
  1. aAntimicrobial breakpoints that distinguish susceptible from resistant gonococcal isolates (CLSI Document M07-A9 (M100-S22) [35]. MIC: minimum inhibitory concentration.