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Table 2 Baseline characteristics of the ITT patients enrolled in the three treatment groups of the trial

From: A randomized controlled phase IIb wound healing trial of cutaneous leishmaniasis ulcers with 0.045% pharmaceutical chlorite (DAC N-055) with and without bipolar high frequency electro-cauterization versus intralesional antimony in Afghanistan

  Intention to treat (ITT) evaluation Test
  Group I Group II Group III Total p-value  
Male 14 12 15 41   Pearson Chi-Square
Female 10 17 13 40 0.446* Test (Exact-Sig.)
Age (95% CI) 26 (19-33) 28 (23-33) 32 (25-38) 29 (25-32) 0.252* Kruskal-Wallis Test
Lesion age (95% CI) 9 (7-10) 9 (8-11) 7 (6-8) 8 (7-9) 0.187* Kruskal-Wallis Test
Lesion size (95% CI) 3.6 (2.3-4.9) 2.3 (1.7-3.0) 2.7 (1.8-3.6) 2.8 (2.3-3.4) 0.204* Kruskal-Wallis Test
Parasite species       
L. major 5 7 9 21   
L. tropica 5 14 11 30   Pearson Chi-Square
Not determined 14 8 8 30 0.614* Test (Exact-Sig.)
Lesion location       
Head 5 4 4 13   
Trunc 0 0 1 1   
Upper extr. 12 19 16 47   Pearson Chi-Square
Lower extr. 7 5 7 19 0.799* Test (Exact-Sig.)
Parasite load according to Giemsa staining       
Low (+) 13 16 11 40   
Moderate (++) 8 13 16 37   
High (+++) 1 0 1 2   Pearson Chi-Square
Not determined 2 0 0 2 0.534* Test (Exact-Sig.)
Biopsy prior to treatment       
Evaluable 17 23 22 62   Pearson Chi-Square
Not evaluable 7 6 6 19 0.800* Test (Exact-Sig.)
Parasite load/g tissue (SEM) 2.773 (1.554)x106 3.430 (1.736)x106 2.368 (1.526)x106 2.889 (0.932)x106 0.691* Kruskal-Wallis Test
  1. Statistical tests were used as indicated (p < 0.05 indicates a significant proportion, * p-values refer to observations with complete information).