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Table 1 SIRS patients- Nosocomial ICU acquired RGNB Infection and patients with no GNB: Patient characteristics and univariate analysis

From: A prediction tool for nosocomial multi-drug resistant gram-negative bacilli infections in critically ill patients - prospective observational study

  No GNB* Infection/colonization (n = 1398) RGNB Infection (n = 76) p -value
Gender, n (%)    0.49
Male 902 (64.5%) 52 (68.4%)  
Female 496 (35.5%) 24 (31.6%)  
Age, years (mean, ±SD) 56.9 (SD17.8) 59.7 (SD17.6) 0.19
APACHEII (median, range) 17 (1-55) 19 (2-39) 0.03
Intensive care unit, n (%)    0.02
Medical 868 (62.9%) 37 (49.3%)  
Surgical 513 (37.1%) 38 (50.7%)  
Comorbidities, n (%)    
Diabetes Mellitus 427 (30.5%) 24 (31.6%) 0.85
Dialysis with end stage renal disease 130 (9.3%) 14 (18.4%) 0.009
Peripheral vascular disease 25 (1.8%) 0 (0%) 0.24
Cerebrovascular accident 207 (14.8%) 8 (10.5%) 0.3
Peptic ulcer disease 67 (4.8%) 4 (5.3%) 0.85
Myocardial Infarction 178 (12.7%) 10 (13.2%) 0.91
Congestive cardiac failure 48 (3.4%) 4 (5.3%) 0.4
Liver disease 52 (3.7%) 3 (3.9%) 0.92
Leukemia 34 (2.4%) 4 (5.3%) 0.13
Malignancy 163 (11.7%) 9 (11.8%) 0.96
Procedure/treatment, n (%)    
Mechanical ventilation 1310 (93.7%) 75 (98.7%) 0.08
Duration of mechanical ventilation 4.5 (SD 4.02) 7.5 (SD 4.9) 0.01
Central venous catheter 920 (65.8%) 58 (76.3%) 0.05
Intra-arterial line 1113 (79.6%) 65 (89.5%) 0.21
Urinary catheter 1156 (82.7%) 70 (92.1% 0.04
Surgery this admission before RGNB 524 (37.5%) 42 (55.3%) 0.002
Transfusion 411 (29.4%) 35 (46.1%) 0.02
Sedation 982 (81%) 67 (91.8%) 0.02
Carbapenems within 6 months 409 (29.3%) 39 (51.3%) <0.001
3rdGeneration Cephalosporins within 6 months 721 (51.6%) 34 (44.7%) 0.25
Other Cephalosporins within 6 months 200 (14.3%) 17 (22.7%) 0.05
Quinolones within 6 months 248 (17.7%) 17 (22.7%) 0.28
Penicillins within 6 months 385 (27.5%) 29 (38.7%) 0.04
Aminoglycosides within 6 months 92 (6.6%) 11 (14.7%) 0.007
Augmentin/Unasyn within 6 months 615 (43.9%) 24 (32%) 0.04
Other antibiotics within 6 months 790 (56.5%) 52 (69.3%) 0.03
Hospitalization in the past one year 246 (17.6%) 19 (25%) 0.1
Median days of pre-ICU stay in the hospital (range) 0 (0-40) 0 (0-29) 0.05
Days of stay in ICU >5 444 (31.8%) 59 (77.6%) <0.001
Cultures, n (%)    
Positive MRSA ll screening on admission to ICU 69 (5.4%) 5 (7.1%) 0.53
Presence of any GNB within 6 months 102 (7.3%) 23 (30.3%) <0.001
  1. *Gram negative bacteria, Resistant gram negative bacteria, Acute Physiology and Chronic Health Evaluation, llMethicillin-resistant Staphylococcus aureus.