Table 1 SIRS patients- Nosocomial ICU acquired RGNB Infection and patients with no GNB: Patient characteristics and univariate analysis

Gender, n (%)

0.49

Male

902 (64.5%)

52 (68.4%)

Female

496 (35.5%)

24 (31.6%)

Age, years (mean, ±SD)

56.9 (SD17.8)

59.7 (SD17.6)

0.19

APACHEII^‡ (median, range)

17 (1-55)

19 (2-39)

0.03

Intensive care unit, n (%)

0.02

Medical

868 (62.9%)

37 (49.3%)

Surgical

513 (37.1%)

38 (50.7%)

Comorbidities, n (%)

Diabetes Mellitus

427 (30.5%)

24 (31.6%)

0.85

Dialysis with end stage renal disease

130 (9.3%)

14 (18.4%)

0.009

Peripheral vascular disease

25 (1.8%)

0 (0%)

0.24

Cerebrovascular accident

207 (14.8%)

8 (10.5%)

0.3

Peptic ulcer disease

67 (4.8%)

4 (5.3%)

0.85

Myocardial Infarction

178 (12.7%)

10 (13.2%)

0.91

Congestive cardiac failure

48 (3.4%)

4 (5.3%)

0.4

Liver disease

52 (3.7%)

3 (3.9%)

0.92

Leukemia

34 (2.4%)

4 (5.3%)

0.13

Malignancy

163 (11.7%)

9 (11.8%)

0.96

Procedure/treatment, n (%)

Mechanical ventilation

1310 (93.7%)

75 (98.7%)

0.08

Duration of mechanical ventilation

4.5 (SD 4.02)

7.5 (SD 4.9)

0.01

Central venous catheter

920 (65.8%)

58 (76.3%)

0.05

Intra-arterial line

1113 (79.6%)

65 (89.5%)

0.21

Urinary catheter

1156 (82.7%)

70 (92.1%

0.04

Surgery this admission before RGNB

524 (37.5%)

42 (55.3%)

0.002

Transfusion

411 (29.4%)

35 (46.1%)

0.02

Sedation

982 (81%)

67 (91.8%)

0.02

Carbapenems within 6 months

409 (29.3%)

39 (51.3%)

<0.001

3rdGeneration Cephalosporins within 6 months

721 (51.6%)

34 (44.7%)

0.25

Other Cephalosporins within 6 months

200 (14.3%)

17 (22.7%)

0.05

Quinolones within 6 months

248 (17.7%)

17 (22.7%)

0.28

Penicillins within 6 months

385 (27.5%)

29 (38.7%)

0.04

Aminoglycosides within 6 months

92 (6.6%)

11 (14.7%)

0.007

Augmentin/Unasyn within 6 months

615 (43.9%)

24 (32%)

0.04

Other antibiotics within 6 months

790 (56.5%)

52 (69.3%)

0.03

Hospitalization in the past one year

246 (17.6%)

19 (25%)

0.1

Median days of pre-ICU stay in the hospital (range)

0 (0-40)

0 (0-29)

0.05

Days of stay in ICU >5

444 (31.8%)

59 (77.6%)

<0.001

Cultures, n (%)

Positive MRSA ^ll screening on admission to ICU

69 (5.4%)

5 (7.1%)

0.53

Presence of any GNB within 6 months

102 (7.3%)

23 (30.3%)

<0.001