Table 5 Univariate analysis of outcome in elderly patients with candidemia

Age ≥85 years^a

4 (20.0)

5 (11.6)

0.619

Male sex

17 (85.0)

34 (79.1)

0.831

Solid tumor^a

8 (40.0)

7 (16.3)

0.082

Diabetes mellitus

8 (40.0)

16 (37.2)

0.832

Chronic renal failure

9 (45.0)

9 (20.9)

0.049

Prior immunosuppressive drugs

5 (25.0)

11 (25.6)

0.961

Severe hypoalbuminemia

8 (40.0)

5 (11.6)

0.040

Surgery^a

5 (25.0)

9 (20.9)

0.971

ICU stay ≥5 days

9 (45.0)

10 (23.3)

0.080

Parental nutrition

7 (35.0)

13 (30.2)

0.705

Receipt of mechanical ventilation

14 (70.0)

13 (30.2)

0.003

CVC placement

9 (45.0)

23 (53.5)

0.530

CVC-related candidemia^a

1 (5.0)

7 (16.3)

0.398

CVC removal^a

1 (5.0)

13 (30.2)

0.055

Antifungal therapy administered before microbiological documentation

3 (15.0)

19 (44.2)

0.024

 Prophylactic treatment^a

1 (5.0)

6 (14.0)

0.534

 Empiric treatment^a

2 (10.0)

10 (23.3)

0.367

Antifungal therapy administered/changed after microbiological documentation

8 (40.0)

20 (46.5)

0.628

Triazoles usage

9 (45.0)

27 (62.8)

0.184

Echinocandins usage ^a

2 (10.0)

12 (27.9)

0.206

Absence of antifungal therapies

10 (50.0)

6 (14.0)

0.002

Platelet count ×100 g/L × 10⁹/L

7 (35.0)

5 (11.6)

0.028

Serum creatinine level ≥180 μmol/L

8 (40.0)

7 (16.3)

0.040

Total bilirubin level ≥30 μmol/L

9 (45.0)

7 (16.3)

0.015

Concurrent bacteraemia

6 (30.0)

2 (4.7)

0.016

APACHE II score ≥20

15 (75.0)

16 (37.2)

0.005

Septic shock

13 (65.0)

14 (32.6)

0.015