Table 1 Demographics and clinical risk factors of the elderly and younger patients with candidemia
Characteristics | Elderly patients (≥65 years, n =63) | Younger patients (16–60 years, n =84) | p value |
|---|---|---|---|
Age (years)a | 75.4 ± 12.7 | 39.6 ± 11.2 | <0.001 |
Male sex | 51 (81.0) | 59 (70.2) | 0.139 |
Length of staya | 45.3 ± 32.8 | 39.2 ± 30.9 | 0.251 |
Hospital settings | Â | Â | Â |
 ICUs | 31 (49.2) | 20 (23.8) | 0.001 |
 Medical wards | 14 (22.2) | 32 (38.1) | 0.040 |
 Surgical wards | 12 (19.0) | 25 (29.8) | 0.139 |
 Others | 6 (9.5) | 7 (8.3) | 0.801 |
Host-related risk factors | Â | Â | Â |
 Solid tumour | 15 (23.8) | 5 (6.0) | 0.002 |
 Haematological malignancyb | 3 (4.8) | 14 (16.7) | 0.026 |
 Neutropenia | 5 (7.9) | 20 (23.8) | 0.011 |
 Diabetes mellitus | 24 (38.1) | 8 (9.5) | 0.001 |
 Chronic renal failure | 18 (28.6) | 7 (8.3) | 0.001 |
 Prior immunosuppressive drugs | 16 (25.4) | 25 (29.8) | 0.559 |
 Severe hypoalbuminemia | 13 (20.6) | 10 (11.9) | 0.149 |
Hospital-related risk factors | Â | Â | Â |
 Surgery | 14 (22.2) | 29 (34.5) | 0.105 |
 Abdominal surgical operations | 9 (14.3) | 14 (16.7) | 0.694 |
 ICU stay ≥5 days | 19 (30.2) | 6 (7.1) | 0.001 |
 Multiple blood product transfusion | 8 (12.7) | 16 (19.0) | 0.303 |
 Parental nutrition | 20 (31.7) | 16 (19.0) | 0.076 |
 Receipt of mechanical ventilation | 27 (42.9) | 20 (23.8) | 0.014 |
 CVC placement | 32 (50.8) | 26 (31.0) | 0.015 |
 Urethral catheter placement | 34 (54.0) | 29 (34.5) | 0.018 |
 Prior antibacterial exposureb | 63 (100.0) | 82 (97.6) | 0.607 |
 ≥ 3 kinds of prior antibacterial drugs | 29 (46.0) | 34 (40.5) | 0.501 |