Figure 1From: A novel method for detection of HBVcccDNA in hepatocytes using rolling circle amplification combined with in situ PCR IS-PCR and immunohistochemical staining for detecting HBV cccDNA in FFPE liver biopsies. No positive signal was detected in liver tissue samples from HCV patient (a), healthy adults (b), transgenic mice (c) and HCC patients without specific primers (d) by PSAD + RCA + IS-PCR. Original Magnifications × 200.Back to article page