Table 4 The association between two SNPs within the FTO gene and the risk of tuberculosis stratified by sex
From: Obesity-associated gene FTO rs9939609 polymorphism in relation to the risk of tuberculosis
SNPs | Male (n = 2290) | Female (n = 837) | ||||
|---|---|---|---|---|---|---|
n (%) | OR (95% CI)a | P a | n (%) | OR (95% CI)a | P a | |
rs9939609 (T > A) | ||||||
TT | 1823(79.61) | 1 | 685 (81.84) | 1 | ||
AT | 396(17.29) | 0.93(0.74-1.16) | 0.508 | 132 (15.77) | 0.85(0.58-1.24) | 0.397 |
AA | 71(3.10) | 4.15(2.23-7.70) | <0.001 | 20 (2.39) | 2.46(0.93-6.47) | 0.069 |
Add | 1.27 (1.06-1.51) | 0.008 | 1.09(0.80-1.47) | 0.590 | ||
Dom | 1.13(0.91-1.39) | 0.257 | 0.98(0.68-1.40) | 0.893 | ||
Rec | 4.20(2.27-7.79) | <0.001 | 2.52(0.96-6.63) | 0.061 | ||
rs8050136 (C > A) | ||||||
CC | 1827 (79.78) | 1 | 688 (82.20) | 1 | ||
AC | 448 (19.56) | 1.12(0.90-1.39) | 0.301 | 145 (17.32) | 0.98(0.68-1.42) | 0.924 |
AA | 15 (0.66) | 0.53(0.18-1.52) | 0.237 | 4 (0.48) | 0.35(0.04-3.38) | 0.364 |
Add | 1.06(0.86-1.29) | 0.591 | 0.93(0.66-1.32) | 0.692 | ||
Dom | 1.09(0.88-1.35) | 0.413 | 0.51(0.18-1.49) | 0.220 | ||
Rec | 0.51(0.18-1.49) | 0.220 | 0.35(0.04-3.38) | 0.365 | ||