Table 2 Performance of the Xpert MTB/RIF assay as stratified by clinical application
From: Performance evaluation of the Xpert MTB/RIF assay according to its clinical application
Performance of the Xpert MTB/RIF assay | Total ( n =303) | Clinical application | |||
|---|---|---|---|---|---|
No./Total no.% (95% CI) | Â | Category 1 | Category 2 | Category 3 | Category 4 |
( n =118) | ( n =103) | ( n =19) | ( n =63) | ||
Sensitivity | 95/104 | 53/59 | 2/3 | 11/11 | 29/31 |
91.3 (83.8-95.7) | 89.8 (78.5-95.8 ) | 66.7 (12.5-98.2) | 100 (67.9-100) | 93.5 (77.2-98.9) | |
Specificity | 175/199 | 54/59 | 96/100 | 7/8a | 18/32 |
87.9 (82.4-92.0) | 91.4 (80.3-96.8) | 96.0 (89.5-98.7) | 87.5 (46.7-99.3) | 56.3 (37.9-73.2) | |
PPV | 95/119 | 53/58 | 2/6 | 11/12a | 29/43 |
79.8 (71.3-86.4) | 91.4 (80.3-96.8) | 33.3 (6.0-75.9) | 91.7 (59.8-99.6) | 67.4 (51.3-80.5) | |
NPV | 175/184 | 54/60 | 96/97 | 7/7 | 18/20 |
95.1 (90.6-97.6) | 90.0 (78.8-95.9) | 99.0 (93.6-99.9) | 100 (56.1-100) | 90.0 (66.9-98.2) | |