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Table 5 Multivariate models for correlates of HPV16 seroreactivity*

From: Determinants of baseline seroreactivity to human papillomavirus type 16 in the Ludwig-McGill cohort study

Variable Categories Model 1 Model 2
Age (years) <25 1.0 1.0
25-34 1.36 (0.94-1.97) 1.52 (1.1-2.2)
35-44 1.73 (1.15-2.61) 1.91 (1.28-2.87)
45+ 2.41 (1.48-3.93) 3.07 (1.86-5.06)
Income 1st Quartile 1.0  
2nd Quartile 0.88 (0.63-1.23)  
3rd Quartile 0.81 (0.58-1.13)  
4th Quartile 0.78 (0.57-1.06)  
Smoking duration Never 1.0  
<10 years 0.71 (0.52-0.95)  
> = 10 years 0.59 (0.44-0.79)  
Lifetime sexual partners 0-1 1.0 1.0
2-3 1.76 (1.33-2.32) 1.44 (1.05-1.96)
4-5 2.69 (1.89-3.84) 2.06 (1.39-3.05)
6+ 2.18 (1.40-3.4) 1.74 (1.09-2.79)
Age at first sexual intercourse 20-50 1.0 1.0
18-19 1.50 (1.05-2.14) 1.46 (1.00-2.12)
16-17 1.41 (0.98-2.03) 1.36 (0.94-1.96)
<=15 1.64 (1.13-2.40) 1.71 (1.18-2.48)
Frequency of sex (weekly) 0-1 1.0 1.0
2-3 1.07 (0.83-1.39) 1.05 (0.79-1.38)
4-5 1.63 (1.07-2.47) 1.60 (1.05-2.45)
6+ 1.57 (0.96-2.66) 1.72 (1.01-2.94)
Condom Use Never 1.0  
Rarely 1.00 (0.73-1.35)  
Sometimes/always 0.77 (0.57-1.02)  
Parity 0-1 1.0  
2-4 1.20 (0.84-1.71)  
5+ 1.38 (0.86-1.95)  
HPV16 viral load Negative 1.0 1.0
<1 2.42 (0.88-6.76) 4.16 (1.35-12.78)
1-100 4.19 (1.84-9.56) 4.03 (1.48-10.45)
100+ 3.73 (1.10-12.6) 3.18 (0.78-12.98)
HPV16 DNA co-infection No HPV16 1.0  
HPV16 alone 3.53 (1.76-7.10)  
HPV16 + other type 3.30 (1.25-8.63)  
  1. *Model 1: Mutually adjusted for all variables shown; model 2: most parsimonious set of independently explanatory variables via stepwise regression with backwards elimination (due to collinearity issues between HPV16 and viral load, only HPV16 viral load was retained as covariate for the models shown).