Figure 5

Anti-HCV status of HCV monoinfection, HCV/HIV coinfection with CD4 ≥ 500/mm ³ and coinfection with CD4 < 500/mm ³ were performed by Architect anti-HCV assay and HCV-RIBA assay respectively. (A) S/CO ratios of anti-HCV antibody of HCV/HIV-1-coinfected patients with CD4+ T <500/mm³ were significantly lower than coinfected patients with CD4+ T ≥500/ mm³and HCV-monoinfected patients. (B) Anti-HCV responses induced by Core, NS3, NS4 and NS5 proteins of HCV monoinfection, HCV/HIV coinfection with CD4 ≥ 500/mm³ and coinfection with CD4 < 500/mm³ were retested by HCV-RIBA assay. The intensity of the HCV bands is scored in relation to the intensities of the internal IgG controls as 5 different levels: 0(none), +, ++, +++, ++++, according to the manufacturer's instructions. Mann Whitney U-tests were performed, p < 0.05 indicates significance.