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Table 3 Clinical diagnostic tests based on main predictor variables associated with influenza among military trainees with febrile respiratory illness

From: Retrospective analysis of demographic and clinical factors associated with etiology of febrile respiratory illness among US military basic trainees

Clinical predictor(s)

SN (%) (95% CI)

SP (%) (95% CI)

PPV (%) (95% CI)

NPV (%) (95% CI)

Cough

98.3 (97-98)

11.4 (10-11)

7.3 (6-7)

98.9 (98-99)

Fever

85.9 (83-87)

17.1 (16-17)

6.9 (6-7)

94.4 (93-95)

Training week 0-2

54.0 (51-56)

84.0 (83-84)

19.4 (18-20)

96.2 (95-96)

Acute onset

73.9 (71-76)

41.9 (41-42)

8.3 (7-8)

95.7 (95-96)

Body aches

74.8 (72-77)

29.3 (28-29)

7.0 (6-7)

94.2 (93-94)

Winter

50.7 (48-53)

77.6 (77-78)

13.9 (12-14)

95.7 (95-95)

Cough + fever

84.3 (82-86)

27.1 (26-27)

7.6 (7-8)

96.0 (95-96)

Cough + training week 0-2

53.4 (50-56)

85.9 (85-86)

21.3 (19-22)

96.3 (96-96)

Cough + training week 0-2 + fever

43.7 (41-46)

89.4 (88-89)

22.7 (21-24)

95.7 (95-95)

Cough + training week 0-2 + fever + acute onset

33.2 (30-35)

93.9 (93-94)

27.9 (25-30)

95.2 (94-95)

Training week 0-2 + winter

9.3 (7-10)

95.4 (95-95)

12.6 (10-14)

93.7 (93-93)

Cough + training week 0-2 + winter

33.9 (31-36)

95.8 (95-96)

36.3 (33-38)

95.3 (95-95)

Cough + training week 0-2 + winter + fever

26.9 (24-29)

97.0 (96-97)

39.4 (36-42)

94.9 (94-95)

  1. NOTE. Predictor variables were added to diagnostic test based on descending order of significance with outcome variable (influenza) on multivariate logistic regression results. Influenza was compared with other FRI (non-adenovirus confirmed, non-influenza confirmed) and adenovirus confirmed.
  2. CI, confidence interval, calculated with binomial expansion; NPV, negative predictive value; PPV, positive predictive value; SN, sensitivity; SP, specificity.