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Table 2 Clinical diagnostic tests based on main predictor variables associated with adenovirus among military trainees with febrile respiratory illness

From: Retrospective analysis of demographic and clinical factors associated with etiology of febrile respiratory illness among US military basic trainees

Clinical predictor(s)

SN (%) (95% CI)

SP (%) (95% CI)

PPV (%) (95% CI)

NPV (%) (95% CI)

Sore throat

93.0 (92-93)

18.4 (17-19)

66.6 (65-67)

60.2 (58-62)

Cough

91.5 (91-91)

14.7 (13-15)

65.2 (64-65)

49.8 (47-51)

Fever

87.0 (86-87)

23.9 (22-24)

66.7 (65-67)

51.3 (49-52)

Summer

32.8 (32-33)

73.4 (72-74)

68.5 (67-69)

38.3 (37-39)

Training week 5 & 6

30.2 (29-30)

83.5 (82-84)

76.2 (75-77)

40.6 (39-41)

Fall

24.9 (24-25)

78.8 (77-79)

67.3 (65-68)

37.5 (36-38)

Training week 3 & 4

38.8 (38-39)

76.9 (75-77)

74.6 (73-75)

41.8 (41-42)

Training week 3-6

70.0 (69-70)

59.4 (58-60)

75.3 (74-76)

52.9 (51-53)

Spring

22.9 (22-23)

80.5 (79-81)

67.3 (65-68)

37.4 (36-38)

Sore throat + cough

85.3 (84-85)

30.6 (29-31)

68.3 (67-68)

54.4 (52-55)

Sore throat + fever

81.2 (80-81)

36.7 (35-37)

69.2 (68-69)

52.7 (51-54)

Sore throat + cough + fever

74.4 (73-75)

47.3 (46-48)

71.2 (70-71)

51.4 (50-52)

Sore throat + cough + fever + summer

24.2 (23-24)

86.3 (85-87)

75.5 (74-76)

39.4 (38-40)

Sore throat + cough + fever + training week 3-6

52.8 (51-53)

79.0 (78-79)

81.5 (80-82)

48.9 (48-49)

Sore throat + fever + summer

26.7 (25-27)

83.0 (82-83)

73.4 (72-74)

39.3 (38-40)

Sore throat + fever + training week 3-6

56.7 (55-57)

75.4 (74-76)

80.1 (79-80)

49.9 (48-50)

Sore throat + fever + training week 3-6 + summer

19.5 (18-20)

92.4 (91-92)

81.7 (80-82)

39.6 (38-40)

  1. NOTE. Predictor variables were added to diagnostic test based on descending order of significance with outcome variable (influenza) on multivariate logistic regression results. Adenovirus was compared with FRI other (non-adenovirus confirmed, non-influenza confirmed) and influenza confirmed.
  2. CI, confidence interval, calculated with binomial expansion; NPV, negative predictive value; PPV, positive predictive value; SN, sensitivity; SP, specificity.