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Table 3 Ventilation characteristics at day 1 and 7 of colonization

From: Safety and efficacy of amphotericin-B deoxycholate inhalation in critically ill patients with respiratory Candida spp. colonization: a retrospective analysis

 

ABDC no n = 62

ABDC yes n = 51

P

Tidal volume, ml/kg, day 1

7 (2)

7 (2)

0.77

Tidal volume, ml/kg, day 7

7 (3)

8 (3)

0.50

PEEP, cm H2O, day 1

9 (4)

9 (4)

0.10

PEEP, cm H2O, day 7

6 (5)

10 (6)

0.004

Compliance, mL/cm H2O, day 1

37 (28)

44 (39)

0.05

Compliance, mL/cm H2O, day 7

40 (27)

41 (36)

0.09

PaO2/ FIO2 ratio, day 1

213 (122)

197 (137)

0.40

PaO2/ FIO2 ratio, day 7

282 (123)

217 (147)

0.005

Chest X-ray, no. of quadrants, day 1

2 (2)

2 (1)

0.27

Chest X-ray, no. of quadrants, day 7

2 (3)

2 (2)

0.41

LIS, day 1

2.0 (1.0)

1.8 (1.3)

0.47

LIS, day 7

1.0 (1.3)

1.8 (1.5)

0.002

Ventilation after day 1, days

7 (9)

20 (16)

<0.001

  1. Numbers (percentage) or median (interquartile range), where appropriate. Abbreviations: ABDC = amphotericin B deoxycholate; PEEP = positive end-expiratory pressure; PaO2 = partial pressure of oxygen in the blood (kPa); FIO2 = the percentage of oxygen administered; LIS = lung injury score; day 1 and 7 refer to day of first isolation of Candida spp. in respiratory secretions and 1 week later, respectively.