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Table 1 Patient characteristics at admission, day 1 of colonization and clinical course

From: Safety and efficacy of amphotericin-B deoxycholate inhalation in critically ill patients with respiratory Candida spp. colonization: a retrospective analysis

 

ABDC no n = 62

ABDC yes n = 51

P

Age, years

57 (17)

58 (20)s

0.62

Gender, male

34 (55)

37 (73)

0.05

Premorbidity

   

 Cardiac

31 (50)

18 (35)

0.12

 Gastointestinal

21 (34)

24 (47)

0.16

 Cancer

17 (27)

16 (31)

0.65

 Pulmonary

16 (26)

13 (25)

0.97

 Neurological

11 (18)

12 (24)

0.45

 DM

12 (19)

8 (16)

0.61

 Renal

5 (8)

9 (18)

0.14

 Immune

2 (3)

0 (0)

0.16

 Other

20 (32)

14 (27)

0.58

Reasons of ICU admission

  

0.28

 Suspected infection

18 (29)

18 (35)

 

 Respiratory failure

9 (15)

13 (25)

 

 Shock

9 (15)

6 (12)

 

 Neurological

11 (18)

4 (8)

 

 Medical

3 (5)

3 (6)

 

 Postoperative

6 (9)

4 (8)

 

 CPR

4 (6)

1 (2)

 

 Trauma

2 (3)

2 (4)

 

SAPS II

43 (18)

48 (16)

0.12

At day 1 of colonization

APACHE II

21 (12)

20 (9)

0.21

SOFA

9 (6)

9 (5)

0.18

Days from admission ICU

1 (3)

1 (2)

0.64

Ventilation from admission, days

1 (2)

1 (3)

0.18

Course

Duration of stay ICU, days

10 (12)

24 (18)

<0.001

28-day mortality

19 (32)

10 (20)

0.13

90-day mortality

27 (45)

19 (37)

0.40

  1. Numbers (percentage) or median (interquartile range), where appropriate. Abbreviations: ABDC = amphotericin-B deoxycholate; DM = diabetes mellitus; ICU = intensive care unit; CPR = cardiac pulmonary resuscitation; SAPS II = simplified acute physiology score; APACHE II = acute physiology and chronic health evaluation II; SOFA = sequential organ failure assessment score.