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Table 1 Patient characteristics at admission, day 1 of colonization and clinical course

From: Safety and efficacy of amphotericin-B deoxycholate inhalation in critically ill patients with respiratory Candida spp. colonization: a retrospective analysis

  ABDC no n = 62 ABDC yes n = 51 P
Age, years 57 (17) 58 (20)s 0.62
Gender, male 34 (55) 37 (73) 0.05
Premorbidity    
 Cardiac 31 (50) 18 (35) 0.12
 Gastointestinal 21 (34) 24 (47) 0.16
 Cancer 17 (27) 16 (31) 0.65
 Pulmonary 16 (26) 13 (25) 0.97
 Neurological 11 (18) 12 (24) 0.45
 DM 12 (19) 8 (16) 0.61
 Renal 5 (8) 9 (18) 0.14
 Immune 2 (3) 0 (0) 0.16
 Other 20 (32) 14 (27) 0.58
Reasons of ICU admission    0.28
 Suspected infection 18 (29) 18 (35)  
 Respiratory failure 9 (15) 13 (25)  
 Shock 9 (15) 6 (12)  
 Neurological 11 (18) 4 (8)  
 Medical 3 (5) 3 (6)  
 Postoperative 6 (9) 4 (8)  
 CPR 4 (6) 1 (2)  
 Trauma 2 (3) 2 (4)  
SAPS II 43 (18) 48 (16) 0.12
At day 1 of colonization
APACHE II 21 (12) 20 (9) 0.21
SOFA 9 (6) 9 (5) 0.18
Days from admission ICU 1 (3) 1 (2) 0.64
Ventilation from admission, days 1 (2) 1 (3) 0.18
Course
Duration of stay ICU, days 10 (12) 24 (18) <0.001
28-day mortality 19 (32) 10 (20) 0.13
90-day mortality 27 (45) 19 (37) 0.40
  1. Numbers (percentage) or median (interquartile range), where appropriate. Abbreviations: ABDC = amphotericin-B deoxycholate; DM = diabetes mellitus; ICU = intensive care unit; CPR = cardiac pulmonary resuscitation; SAPS II = simplified acute physiology score; APACHE II = acute physiology and chronic health evaluation II; SOFA = sequential organ failure assessment score.