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Table 1 Sociodemographic and clinical characteristics of 161 participants stratified by current HIV-1 RNA

From: Durability of antiretroviral therapy and predictors of virologic failure among perinatally HIV-infected children in Tanzania: a four-year follow-up

 

Total(N = 161)

HIV-1 RNA<400 copies/mL(N = 118)

HIV-1 RNA >400 copies/mL(N = 43)

Gender, N (%)

   

Male

77 (48%)

60 (51%)

17 (40%)

Female

84 (52%)

58 (49%)

26 (60%)

Age (IQR) years

12.2 (9.3 - 15.3)

11.6 (8.8 - 14.6)

13.8 (12.3 - 16.2)

Age (categorical) years

   

Child (≤12 years old)

72 (45%)

63 (53%)

9 (21%)

Adolescent (>12 years old)

89 (55%)

55 (47%)

34 (79%)

Time on Treatment (IQR) years

6.4 (5.3 - 7.5)

6.3 (5.2 - 7.4)

6.6 (5.5 - 7.6)

1st Line Regimen

AZT or (d4T) +3TC + EFV

35 (21%)

28 (24%)

6 (14%)

AZT or (d4T) + 3TC + NVP

60 (37%)

47 (40%)

13 (30%)

2nd Line Regimen

ABC +3TC + LPV/r

66 (42%)

43 (36%)

24 (56%)

Adherence as reported by physician, N (%)

   

Good

121 (75%)

99 (84%)

22 (51%)

Poor

40 (25%)

19 (16%)

21 (49%)

WHO Stage

   

I

2 (1%)

2 (2%)

0

II

22 (14%)

19 (16%)

3 (7%)

III

92 (57%)

64 (54%)

28 (65%)

IV

45 (28%)

33 (28%)

12 (28%)

+Original HIV-1 RNA, logcopies/mL (IQR)

1.8 (0 - 5.9)

1.6 (0 -5.3)

2.2 (0 - 5.4)

CD4 mean absolute number (IQR)

829 (538 - 1099)

929 (660 - 1160)

530 (224 -784)

++CD4 absolute number by category

   

CD4 < 200, N (%)

9 (5%)

3 (3%)

6 (14%)

CD4 201-349, N (%)

13 (8%)

4 (3%)

9 (21%)

CD4 350 - 499, N (%)

13 (8%)

7 (6%)

6 (14%)

CD4 ≥ 500, N (%)

112 (70%)

96 (81%)

16 (37%)

CD4 missing, N (%)

14 (9%)

8 (7%)

6 (14%)

  1. + HIV-1 RNA from 2008-09 log transformed; ++ CD4 categories as defined by WHO.