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Table 5 Predictors of regimen modification due to treatment failure

From: Incidence and predictors of regimen-modification from first-line antiretroviral therapy in Thailand: a cohort study

  HRa(95% CIb) P aHRc(95% CIb) P
Gender     
  Male 1   1  
  Female 0.61 (0.36-1.01) 0.06 0.54 (0.30-0.96) 0.04
Age 1   1  
  <35
  ≥35 0.54 (0.32-0.92) 0.02 0.56 (0.32-0.99) 0.05
Clinical status     
  Asymptomatic 1   1  
  Symptomatic 1.29 (0.51-3.23) 0.59 1.19 (0.47-3.00) 0.72
  AIDS 0.92 (0.39-2.20) 0.86 0.73 (0.29-1.85) 0.51
CD4 cell count     
  >200 1   1  
  50-199 0.74 (0.28-1.94) 0.55 0.59 (0.22-1.55) 0.28
  <50 0.82 (0.32-1.12) 0.68 0.68 (0.25-1.86) 0.45
HLA-B*40:01     
  No 1   1  
  Yes 0.38 (0.16-0.87) 0.02 0.29 (0.10-0.82) 0.02
  1. aHR, hazard ratio.
  2. bCI, confidence interval.
  3. caHR, adjusted hazard ratio.