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Table 5 Predictors of regimen modification due to treatment failure

From: Incidence and predictors of regimen-modification from first-line antiretroviral therapy in Thailand: a cohort study

 

HRa(95% CIb)

P

aHRc(95% CIb)

P

Gender

    

  Male

1

 

1

 

  Female

0.61 (0.36-1.01)

0.06

0.54 (0.30-0.96)

0.04

Age

1

 

1

 

  <35

  ≥35

0.54 (0.32-0.92)

0.02

0.56 (0.32-0.99)

0.05

Clinical status

    

  Asymptomatic

1

 

1

 

  Symptomatic

1.29 (0.51-3.23)

0.59

1.19 (0.47-3.00)

0.72

  AIDS

0.92 (0.39-2.20)

0.86

0.73 (0.29-1.85)

0.51

CD4 cell count

    

  >200

1

 

1

 

  50-199

0.74 (0.28-1.94)

0.55

0.59 (0.22-1.55)

0.28

  <50

0.82 (0.32-1.12)

0.68

0.68 (0.25-1.86)

0.45

HLA-B*40:01

    

  No

1

 

1

 

  Yes

0.38 (0.16-0.87)

0.02

0.29 (0.10-0.82)

0.02

  1. aHR, hazard ratio.
  2. bCI, confidence interval.
  3. caHR, adjusted hazard ratio.