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Table 4 Predictors of regimen modification due to rash

From: Incidence and predictors of regimen-modification from first-line antiretroviral therapy in Thailand: a cohort study

  HRa(95% CIb) P aHRc(95% CIb) P
Gender     
  Male 1   1  
  Female 1.83 (1.03-3.27) 0.04 1.82 (0.99-3.34) 0.05
Age     
  <35 1   1  
  ≥35 1.20 (0.69-2.10) 0.51 1.08 (0.60-1.93) 0.81
Clinical status     
  Asymptomatic 1   1  
  Symptomatic 0.45 (0.19-1.09) 0.08 0.52 (0.21-1.28) 0.15
  AIDS 0.61 (0.31-1.22) 0.16 0.94 (0.44-2.03) 0.88
CD4 cell count     
  >200 1 0.75 1 0.60
  50-199 1.21 (0.37-3.98) 1.38 (0.41-4.63)
  <50 0.70 (0.21-2.39) 0.58 0.71 (0.20-2.55) 0.60
HLA-B*35:05     
  No 1   1  
  Yes 8.24 (3.51-19.4) <0.001 7.73 (3.16-18.9) <0.001
HLA-B*57:01     
No 1   1  
Yes 1.70 (0.23-12.3) 0.60 2.06 (0.28-15.4) 0.48
  1. aHR, hazard ratio.
  2. bCI, confidence interval.
  3. caHR, adjusted hazard ratio.