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Table 3 Predictors of regimen modification due to lipodystrophy

From: Incidence and predictors of regimen-modification from first-line antiretroviral therapy in Thailand: a cohort study

 

HRa(95% CIb)

P

aHRc(95% CIb)

P

Gender

    

  Male

1

 

1

 

  Female

2.05 (1.50-2.79)

<0.001

2.11 (1.51-2.95)

<0.001

Age

    

  <35

1

 

1

 

  ≥35

1.12 (0.83-1.51)

0.46

1.35 (0.98-1.84)

0.06

Clinical status

    

  Asymptomatic

1

 

1

 

  Symptomatic

0.88 (0.54-1.45)

0.62

0.81 (0.48-1.36)

0.43

  AIDS

0.65 (0.41-1.03)

0.07

0.72 (0.43-1.21)

0.21

CD4 cell count

    

  >200

1

 

1

 

  50-199

0.85 (0.46-1.57)

0.61

0.95 (0.50-1.80)

0.87

  <50

0.80 (0.43-1.46)

0.46

1.08 (0.56-2.07)

0.83

HLA-B*40:01

    

  No

1

 

1

 

  Yes

0.92 (0.64-1.32)

0.64

0.91 (0.62-1.32)

0.62

  1. aHR, hazard ratio.
  2. bCI, confidence interval.
  3. caHR, adjusted hazard ratio.