From: Diabetes does not affect outcome in patients with Enterobacteriaceae bacteremia
Exitus n = 70 | Surviving n = 894 | p-value | RR (95% CI) | |
---|---|---|---|---|
Demographics | ||||
Male | 39 (55.7) | 479 (53.7) | 0.8 | 1.08 (0.69–1.7) |
Age, years (mean ± SD) | 78.1 ± 12.8 | 70.1 ± 16.5 | <0.001 | |
Severe sepsis or shock | 41 (58.6) | 91 (10.2) | <0.001 | 8.91 (5.75–13.82) |
Adequate empirical antibiotic | 47 (68.1) | 746 (83.6) | 0.002 | 0.45 (0.28–0.73) |
Blood glucose concentration, mg/dL (mean ± SD) | 170.9 ± 80.4 | 158.6 ± 70.2 | 0.44 | |
Comorbidities | ||||
COPD** | 5 (7.1) | 86 (9.6) | 0.67 | 0.74 (0.31–1.78) |
Ictus | 6 (8.6) | 49 (5.5) | 0.28 | 1.55 (0.7–3.42) |
Cirrhosis | 7 (10) | 46 (5.1) | 0.08 | 1.91 (0.84–1.04) |
Chronic renal failure | 3 (4.3) | 27 (3) | 0.47 | 1.39 (0.47–4.18) |
Immunosuppression | 8 (11.4) | 37 (4.1) | 0.01 | 2.64 (1.35–5.16) |
Cardiac failure | 6 (8.6) | 36 (4) | 0.08 | 2.06 (0.95–4.48) |
Diabetes | 10 (14.3) | 146 (16.3) | 0.4 | 0.86 (0.45–1.65) |
Origin of infection | ||||
Urinary | 18 (26.5) | 511 (57.1) | <0.001 | 0.3 (0.18–0.5) |
Biliary | 13 (19.1) | 163 (18.2) | 0.87 | 1.06 (0.59–1.89) |
Unknown | 16 (23.5) | 120 (13.4) | 0.03 | 1.87 (1.1–3.18) |
Intraabdominal | 5 (7.4) | 33 (3.7) | 0.18 | 1.93 (0.83–4.52) |
Pneumonia | 9 (13.2) | 13 (1.5) | <0.001 | 6.53 (3.73–11.42) |
Microorganism | ||||
E. coli | 48 (68.6) | 716 (79.8) | 0.03 | 0.58 (0.36–0.94) |
Klebsiella spp. | 5 (7.1) | 54 (6) | 0.43 | 1.18 (0.5–2.83) |
Proteus spp. | 4 (5.7) | 44 (4.9) | 0.46 | 1.16 (0.44–3.05) |
Citrobacter spp. | 2 (2.9) | 8 (0.9) | 0.16 | 2.82 (0.8–9.93) |
Enterobacter spp. | 3 (4.3) | 21 (2.3) | 0.25 | 1.76 (0.6–5.2) |
Serratia marcescens | 2 (2.9) | 4 (0.4) | 0.06 | 4.71 (1.49–14.95) |
Morganella morgagnii | 1 (1.4) | 8 (0.9) | 0.49 | 1.54 (0.24–9.93) |
Salmonella spp. | 5 (7.1) | 37 (4.1) | 0.18 | 1.69 (0.72–3.99) |
Polymicrobial | 11 (15.7) | 68 (7.6) | 0.02 | 2.09 (1.15–3.82) |