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Table 3 Risk factors for mortality in patients with nosocomial bacteremia

From: Diabetes does not affect outcome in patients with Enterobacteriaceae bacteremia

 

Exitus

n = 19

Surviving

n = 124

p-value

RR* (95% CI)

Demographics

   Male

15 (78.9)

76 (61.3)

0.03

2.14 (0.75–6.12)

   Age, years (mean ± SD)

73 ± 9.27

71.9 ± 13.75

0.01

 

Severe sepsis or shock

11 (57.9)

19 (15.2)

<0.001

5.18 (2.31–11.8)

Adequate empirical antibiotic

16 (80)

93 (78.8)

0.59

1.37 (0.43–4.38)

Blood glucose concentration, mg/dL (mean ± SD)

138.2 ± 58.1

144.8 ± 64.8

0.95

 

Comorbidities

   COPD**

5 (26.3)

17 (13.7)

0.17

1.96 (0.75–4.71)

   Ictus

2 (10.5)

6 (4.8)

0.29

1.99 (0.56–7.19)

   Cirrhosis

0

8 (6.4)

0.6

 

   Chronic renal failure

5 (26.3)

1 (0.8)

<0.001

8.16 (4.42–15.04)

   Immunosuppression

2 (10.5)

5 (4)

0.23

2.29 (0.65–8)

   Cardiac failure

5 (26.3)

12 (9.7)

0.05

2.65 (1.09–6.43)

   Diabetes

3 (15.8)

21 (16.9)

0.6

0.93 (0.29–2.94)

Origin of infection

   Urinary

1 (5)

50 (40.3)

0.002

0.1 (0.01–0.72)

   Biliary

2 (10.5)

22 (17.9)

0.34

1.07 (0.93–1.23)

   Unknown

6 (30)

24 (20)

0.24

1.72 (0.72–4.15)

   Intraabdominal

2 (10.5)

18 (14.6)

1

0.72 (0.18–2.87)

   Pneumonia

5 (26.3)

3 (2.4)

0.001

5.67 (2.76–11.62)

Microorganism

   E. coli

8 (42.1)

89 (71.2)

0.01

0.34 (0.15–0.8)

   Klebsiella spp.

4 (20)

19 (15.2)

0.51

1.39 (0.51–3.82)

   Proteus spp.

1 (5.3)

3 (2.4)

0.44

1.93 (0.34–11.12)

   Citrobacter spp.

1 (0.8)

0

0.86

 

   Enterobacter spp.

3 (15.8)

9 (7.3)

0.2

2.05 (0.69–6.04)

   Serratia marcescens

0

3 (2.4)

1

 

   Morganella morgagnii

2 (10.5)

1 (0.8)

0.05

5.49 (2.19–13.71)

   Salmonella spp.

0

0

  

   Polymicrobial

3 (15)

7 (5.6)

0.13

2.49 (0.87–7.14)

  1. Univariate risk estimates are given
  2. Data are n (%) otherwise indicated
  3. *RR: Relative risk
  4. **COPD: chronic obstructive pulmonary disease