From: Diabetes does not affect outcome in patients with Enterobacteriaceae bacteremia
Exitus n = 90 | Surviving n = 1022 | p-value | RR* (95% CI) | |
---|---|---|---|---|
Demographics | ||||
Male | 55 (61.1) | 558 (54.6) | 0.14 | 1.27 (0.85–1.91) |
Age, years (mean ± SD) | 76.8 ± 12.47 | 70.4 ± 16.2 | <0.001 | |
Severe sepsis or shock | 52 (58.4) | 110 (10.8) | <0.001 | 8.21 (5.57–12.1) |
Adequate empirical antibiotic | 63 (70.8) | 838 (83) | 0.004 | 0.53 (0.34–0.81) |
Blood glucose concentration, mg/dL (mean ± SD) | 164 ± 78 | 157 ± 70 | 0.85 | |
Comorbidities | ||||
COPD** | 10 (11.2) | 104 (10.2) | 0.44 | 1.1 (0.59–2.07) |
Ictus | 8 (9) | 55 (5.4) | 0.13 | 1.64 (0.83–3.24) |
Cirrhosis | 7 (7.9) | 54 (5.3) | 0.21 | 1.47 (0.71–3.03) |
Chronic renal failure | 9 (10) | 28 (2.7) | 0.006 | 2.94 (1.54–5.61) |
Immunosuppression | 10 (11.2) | 42 (4.1) | 0.006 | 2.57 (1.42–4.67) |
Cardiac failure | 11 (12.4) | 49 (4.8) | 0.006 | 2.46 (1.39–4.38) |
Diabetes | 13 (14.6) | 168 (16.5) | 0.39 | 0.88 (0.5–1.54) |
Origin of infection | ||||
Urinary | 19 (21.6) | 561 (55.1) | <0.001 | 0.25 (0.15–0.41) |
Biliary | 16 (18.2) | 185 (18.2) | 0.55 | 1 (0.6–1.68) |
Unknown | 22 (25) | 140 (13.8) | 0.007 | 1.89 (1.20–2.97) |
Intraabdominal | 7 (8) | 52 (5.1) | 0.18 | 1.89 (0.74–3.17) |
Pneumonia | 14 (15.9) | 16 (1.6) | <0.001 | 6.79 (4.37–10.6) |
Microorganism | ||||
E. coli | 57 (63.3) | 805 (78.8) | 0.001 | 0.5 (0.33–0.75) |
Klebsiella spp. | 9 (10) | 73 (7.1) | 0.21 | 1.4 (0.73–2.68) |
Proteus spp. | 5 (5.6) | 47 (4.6) | 0.41 | 1.2 (0.51–2.83) |
Citrobacter spp. | 2 (2.2) | 9 (0.9) | 0.22 | 2.28 (0.64–8.1) |
Enterobacter spp. | 6 (6.7) | 30 (2.9) | 0.06 | 2.14 (1–4.56) |
Serratia marcescens | 2 (2.2) | 7 (0.7) | 0.16 | 2.79 (0.81–9.61) |
Morganella morgagnii | 3 (3.3) | 9 (0.9) | 0.07 | 3.16 (1.16–8.6) |
Salmonella spp. | 5 (5.6) | 37 (3.6) | 0.25 | 1.5 (0.64–3.5) |
Polymicrobial | 14 (15.6) | 76 (7.4) | 0.01 | 2.09 (1.23–3.54) |