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Figure 4 | BMC Infectious Diseases

Figure 4

From: Experimental infection of Balb/c nude mice with Hepatitis E virus

Figure 4

Histopathologic changes in the inoculated group on day 21. A: 1, liver, one of the inoculated nude mice showed an enlarged liver filled with inflammatory exudates, × 200; 2, liver, severe lymphoplasmacytic and histiocytic hepatitis, focal accumulation of inflammatory cells encircling hepatocytes, × 200; 3, spleen, the ruptured and enlarged spleen displaying multiple vacuolar degeneration and focal necrosis, × 200; 4, kidney, the disarranged kidney cells with increased lymphocytes and cellular debris, × 200 B: 5, negative control liver, × 200; 6, negative control liver, × 200; 7, negative control spleen, × 200; 8, negative control kidney, × 200. Tissues were stained with hematoxylin and eosin.

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