Figure 3
From: Experimental infection of Balb/c nude mice with Hepatitis E virus
HEV antigen distribution in tissues of inoculated nude mice detected by indirect immunofluorescence 4d post-inoculation. A: liver, granular fluorescence of HEV antigens distributed throughout hepatocytes, × 200; B: spleen, distinct granular fluorescence of HEV antigens distributed throughout the cytoplasm, especially around the venous sinus, × 100; C: kidney, dozens of HEV antigens surrounding a renal cell, × 200; D: jejunum, distinct granular fluorescence of HEV antigens distributed in the epithelial cells, × 200; E: ileum, granular fluorescence of HEV antigens distributed in the ileum, × 200; F: colon, distinct granular fluorescence of HEV antigens distributed throughout colon, × 100; G: positive control, liver of HEV infected rat, × 100; H: negative control, liver of a nude mouse from the negative control group, × 200.