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Table 3 Comparison of the pre- and post-treatment mean log10 transformed bacterial concentrations and mean log10 – transformed change in concentration within the groups of women treated with oral and vaginal metronidazole.

From: Comparison of oral and vaginal metronidazole for treatment of bacterial vaginosis in pregnancy: impact on fastidious bacteria

Bacteria

 

Oral (n = 30)

Vaginal (n = 23)

L. crispatus

Pre

1.409 ± 1.120a

1.495 ± 1.354

 

Post

1.798 ± 2.056

2.338 ± 2.726

 

Change

.375

(p = .43b)

.843

(p = .17)

G. vaginalis

Pre

6.939 ± 1.577

6.421 ± 1.962

 

Post

5.085 ± 2.449

4.372 ± 2.720

 

Change

-1.853

(p < .01)

-2.049

(p < .01)

Megasphaera spp.

Pre

4.883 ± 2.551

4.587 ± 2.812

 

Post

3.250 ± 2.834

1.970 ± 1.994

 

Change

-1.633

(p < .01)

-2.617

(p < .01)

Leptotrichia/Sneathia

Pre

3.588 ± 2.203

3.211 ± 2.456

 

Post

2.105+2.124

2.331+2.339

 

Change

-1.484

(p < .01)

-.880

(p = .14)

Atopobium

Pre

4.869 ± 2.567

4.715 ± 2.558

 

Post

3.000 ± 2.628

2.598 ± 2.270

 

Change

-1.921

(p < .01)

-2.117

(p < .01)

BVAB1

Pre

2.714 ± 2.699

1.909 ± 2.100

 

Post

1.337 ± 1.340

1.355 ± 1.321

 

Change

-1.378

(p = .026)

-.555

(.127)

BVAB2

Pre

3.343 ± 2.050

2.761 ± 2.294

 

Post

1.601 ± 1.603

1.207 ± .992

 

Change

-1.742

(p < .01)

-1.554

(p < .01)

BVAB3

Pre

1.773+1.589

1.532 ± 1.447

 

Post

1.255 ± .976

1.144 ± .690

 

Change

-1.459

(p = .12)

-.765

(p = .10)

  1. aAll pre- and post-treatment values were compared between groups and were not significantly different.
  2. bAll p-values are for paired T-test comparing pre-treatment concentration of bacterium to post-treatment concentration of bacterium within the individual treatment group.