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Table 3 Comparison of the pre- and post-treatment mean log10 transformed bacterial concentrations and mean log10 – transformed change in concentration within the groups of women treated with oral and vaginal metronidazole.

From: Comparison of oral and vaginal metronidazole for treatment of bacterial vaginosis in pregnancy: impact on fastidious bacteria

Bacteria   Oral (n = 30) Vaginal (n = 23)
L. crispatus Pre 1.409 ± 1.120a 1.495 ± 1.354
  Post 1.798 ± 2.056 2.338 ± 2.726
  Change .375
(p = .43b) 		.843
(p = .17)
G. vaginalis Pre 6.939 ± 1.577 6.421 ± 1.962
  Post 5.085 ± 2.449 4.372 ± 2.720
  Change -1.853
(p < .01) 		-2.049
(p < .01)
Megasphaera spp. Pre 4.883 ± 2.551 4.587 ± 2.812
  Post 3.250 ± 2.834 1.970 ± 1.994
  Change -1.633
(p < .01) 		-2.617
(p < .01)
Leptotrichia/Sneathia Pre 3.588 ± 2.203 3.211 ± 2.456
  Post 2.105+2.124 2.331+2.339
  Change -1.484
(p < .01) 		-.880
(p = .14)
Atopobium Pre 4.869 ± 2.567 4.715 ± 2.558
  Post 3.000 ± 2.628 2.598 ± 2.270
  Change -1.921
(p < .01) 		-2.117
(p < .01)
BVAB1 Pre 2.714 ± 2.699 1.909 ± 2.100
  Post 1.337 ± 1.340 1.355 ± 1.321
  Change -1.378
(p = .026) 		-.555
(.127)
BVAB2 Pre 3.343 ± 2.050 2.761 ± 2.294
  Post 1.601 ± 1.603 1.207 ± .992
  Change -1.742
(p < .01) 		-1.554
(p < .01)
BVAB3 Pre 1.773+1.589 1.532 ± 1.447
  Post 1.255 ± .976 1.144 ± .690
  Change -1.459
(p = .12) 		-.765
(p = .10)
  1. aAll pre- and post-treatment values were compared between groups and were not significantly different.
  2. bAll p-values are for paired T-test comparing pre-treatment concentration of bacterium to post-treatment concentration of bacterium within the individual treatment group.
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BMC Infectious Diseases

ISSN: 1471-2334

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