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Table 1 2008 CDC Lyme Disease Surveillance Case Definition [9]

From: Diagnostic challenges of early Lyme disease: Lessons from a community case series

Confirmed a. a case of EM with a known exposure *
b. a case of EM with laboratory evidence of infection and without a known exposure
c. a case with at least one late manifestation that has laboratory evidence of infection
Probable Any other case of physician-diagnosed Lyme disease that has laboratory evidence of infection
Suspected a. a case of EM where there is no known exposure and no laboratory evidence of infection
b. a case with laboratory evidence of infection but no clinical information available (e.g. a laboratory report)
  1. * exposure is defined as having been (less than or equal to 30 days before onset of EM) in wooded, brushy, or grassy areas (i.e. potential tick habitats) in a county in which Lyme disease is endemic (in which at least two confirmed cases have been acquired in the county or in which established populations of a known tick vector are infected with B. burgdoreri). A history of tick bite is not required.