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Table 3 P. falciparum specific immune responses in parasite free individuals and individuals with sub-microscopic parasite densities by 18S QT-NASBA

From: Low density parasitaemia, red blood cell polymorphisms and Plasmodium falciparumspecific immune responses in a low endemic area in northern Tanzania

  Parasite free individuals Sub-microscopic parasite carriers p-value
MSP-1 IgG antibodies    
prevalence, % (n/N) 68.0 (183/269) 76.7 (89/116) 0.086
median level (IQR) 0.26 (0.14 – 0.79) 0.33 (0.18 – 1.17) 0.042
MSP-2 IgG antibodies    
prevalence, % (n/N) 53.4 (134/251) 58.9 (66/112) 0.33
median level (IQR) 0.32 (0.13 – 0.59) 0.41 (0.19 – 0.72) 0.034
AMA-1 IgG antibodies    
prevalence, % (n/N) 61.0 (153/251) 65.2 (73/122) 0.44
median level (IQR) 0.34 (0.17 – 0.99) 0.48 (0.21 – 1.04) 0.14
  1. Parasitaemia was detected by 18S QT-NASBA and microscopically confirmed parasite carriers were excluded from this table. The optical density in the ELISA was used as indicator of antibody level. P-values are obtained by χ2-test for antibody prevalence or Wilcoxon Rank-sum test for antibody level. The cut-off values for sero-positivity (antibody prevalence) for MSP-1, MSP-2 and AMA-1 were 0.171, 0.292 and 0.252, respectively.