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Table 3 Comparison of Mycoplasma pneumonia with positive PCR from respiratory samples to patients with positive serology results

From: Mycoplasma pneumoniaepneumonia revisited within the German Competence Network for Community-acquired pneumonia (CAPNETZ)

Variables PCR positive
n = 148
Only IgM positive
n = 159
p-value1 Only IgA positive
n = 826
p-value2 Only IgG
positive
n = 973
p-value3
Age ≥ 50 years 23.6% 23.3% .841 67.6% .000 60.5% .000
Male gender 45% 38% .240 58% .003 54% .026
Smoker 29% 42% .017 37% .037 34% .243
Initial treatment setting        
   -outpatient 66% 46% .000 33% .000 39% .000
   -hospitalized 34% 54%   67%   61%  
Fever 68% 59% .081 55% .003 56% .004
Confusion 3% 2% .632 9% .013 8% .023
CRB 65 Score        
0 74% 70% .499 41% .000 46% .000
1–2 22%/4% 29%/1%   42%/13%   38%/12%  
3–4 0 1%/0   2%/1%   3%/1%  
Mechanical ventilation 0 1 patient .332 23 patients .040 20 patients .078
Died within 30 days 1 patient
(0.7%)
1 patient
(0.6%)
.963 62 patients
(7.5%)
.002 61 patients
(6.3%)
.006
  1. Patients with positive PCR were compared to IgM only (column p-values1) positive patients, to patients with only positive IgA (column p-values2) and patients with positive IgG only (column p-values3), respectively. Forty-six patients were positive in PCR and IgM, 55 patients were positive in PCR and IgA and 69 patients were positive in PCR as well as in IgG.