Table 1 Clinical characteristics and antimicrobial treatment of patients with Mycoplasma pneumoniae pneumonia (MPP), CAP due to other bacterial pathogens, and CAP with unknown etiology
Variable | CAP due to other definite bacterial pathogens n = 621 | p1 | MPP n = 307 | p2 | CAP with no known bacterial etiology n = 3604 |
|---|---|---|---|---|---|
Age (∅ ± SD) | 61 ± 17 years | .000 | 41 ± 16 years | .000 | 61 ± 18 years |
Male gender | 58% | .000 | 41% | .000 | 56% |
Outpatient/hospitalized | 22%/78% | .000 | 56%/44% | .000 | 36%/64% |
CRB 65 Score 0-1-2-3-4 (%) | 33-46-16-4-1 | .000 | 72-25-3-0.4-0 | .000 | 39-43-15-2-0.4 |
Packyears(∅ ± SD) | 32 ± 25 | .000 | 15 ± 14 | .000 | 29 ± 23 |
Pleural effusion | 17% | .000 | 6% | .001 | 13% |
Dyspnoea | 80% | .000 | 69% | ns | 72% |
Pleural pain | 47% | .000 | 34% | ns | 42% |
Confusion | 11% | .000 | 2% | .001 | 8% |
Oxygen requirement | 57% | .000 | 25% | .000 | 41% |
Malignancy | 9% | .000 | 2% | .000 | 10% |
Chronic respiratory disease | 38% | .000 | 20% | .000 | 36% |
Renal insufficiency | 8% | .001 | 2% | .000 | 8% |
Congestive heart failure | 19% | .000 | 4% | .000 | 19% |
Diabetes | 20% | .000 | 3% | .000 | 16% |
Respiratory sample obtained* | 42% | .000 | 58% | .000 | 30% |
Leucocytes (median)/μl | 13 200 | .000 | 8850 | .000 | 11 000 |
CRP (median) mg/l | 173 | .000 | 60 | .001 | 73 |
Duration of antibiotic therapy (∅ ± SD) | 13 ± 6 days | .000 | 11 ± 4 days | ns | 11 ± 5 days |
LOS in hospitalized patients (∅ ± SD) | 14 ± 11 days | .000 | 9 ± 5 days | .000 | 12 ± 9 days |
Deaths within 30 days | 54 (8.7%) | .000 | 2 (0.7%) | .000 | 234 (6.5%) |