Figure 6From: A Schistosoma japonicumchimeric protein with a novel adjuvant induced a polarized Th1 immune response and protection against liver egg burdens Effect of different adjuvant on liver egg numbers per female worm. Liver egg numbers per female worm was measured by total number of liver eggs/total number of paired female worm of individual mouse. The reduction rate of liver eggs per female worm was calculated according to the following formula: (1- mean number of liver eggs per female worm in immunized mice/mean number of liver eggs per female worm in control mice) × 100. There was a significant reduction of the number of liver eggs per female in ISA 70M groups at 34.5–37.2%, while the number of liver eggs per female was not significantly reduced in CFA, ISM 1312 and ISA 206 adjuvant groups (Exp 1: 0.6%, 1.9% and -3.2%; Exp 2: -4.1%, -3.4% and -12.5%, respectively). The number of mice per group is from 8 to 10. * p < 0.05 when compared with PBS control group. This picture shows one experiment representative of two independent trials with similar results.Back to article page