Skip to main content

Table 5 Genotype and allele frequencies of tagSNPs in MASP2 in SARS patients and controls from Guangzhou, northern China, and their association with risk of SARS

From: Lack of association between polymorphisms of MASP2and susceptibility to SARS coronavirus infection

 

SARS cases

(n = 104)

Controls

(n = 291)

P value

rs2261695

   

Genotype

   

AA

73(75.3%)

193(70.4%)

0.45

AG

22(22.7%)

78(28.5%)

 

GG

2(2.0%)

3(1.1%)

 

Allele

   

A

168(86.6%)

464(84.7%)

0.52

G

26(13.4%)

84(15.3%)

 

rs2273346

   

Genotype

   

TT

64(61.5%)

190(66.2%)

0.48

TC

36(34.6%)

82(28.6%)

 

CC

4(3.8%)

15(5.2%)

 

Allele

   

T

164(78.8%)

462(80.5%)

0.61

C

44(21.2%)

112(19.5%)

 

rs12711521

   

Genotype

   

TT

58(55.8%)

139(47.8%)

0.25

TG

36(34.6%)

108(37.1%)

 

GG

10(9.6%)

44(15.1%)

 

Allele

   

T

152(73.1%)

386(66.3%)

0.07

G

56(26.9%)

196(33.7%)

 

rs7548659

   

Genotype

   

TT

70(67.3%)

205(70.5%)

0.15

TG

25(24.0%)

75(27.8%)

 

GG

9(8.7%)

11(1.7%)

 

Allele

   

T

165(79.3%)

485(83.3%)

0.19

G

43(20.7%)

97(16.7%)

 

Diplotypea

   

TT

128(61.5%)

380(65.3%)

0.66

TG

42(20.2%)

76(13.0%)

 

CT

4(1.9%)

4(0.7%)

 

CG

34(16.4%)

122(21.0%)

 
  1. aTwo SNP diplotypes span the genomic region of exon 9 (rs2273346 and rs12711521).