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Table 5 Genotype and allele frequencies of tagSNPs in MASP2 in SARS patients and controls from Guangzhou, northern China, and their association with risk of SARS

From: Lack of association between polymorphisms of MASP2and susceptibility to SARS coronavirus infection

  SARS cases (n = 104) Controls (n = 291) P value
rs2261695    
Genotype    
AA 73(75.3%) 193(70.4%) 0.45
AG 22(22.7%) 78(28.5%)  
GG 2(2.0%) 3(1.1%)  
Allele    
A 168(86.6%) 464(84.7%) 0.52
G 26(13.4%) 84(15.3%)  
rs2273346    
Genotype    
TT 64(61.5%) 190(66.2%) 0.48
TC 36(34.6%) 82(28.6%)  
CC 4(3.8%) 15(5.2%)  
Allele    
T 164(78.8%) 462(80.5%) 0.61
C 44(21.2%) 112(19.5%)  
rs12711521    
Genotype    
TT 58(55.8%) 139(47.8%) 0.25
TG 36(34.6%) 108(37.1%)  
GG 10(9.6%) 44(15.1%)  
Allele    
T 152(73.1%) 386(66.3%) 0.07
G 56(26.9%) 196(33.7%)  
rs7548659    
Genotype    
TT 70(67.3%) 205(70.5%) 0.15
TG 25(24.0%) 75(27.8%)  
GG 9(8.7%) 11(1.7%)  
Allele    
T 165(79.3%) 485(83.3%) 0.19
G 43(20.7%) 97(16.7%)  
Diplotypea    
TT 128(61.5%) 380(65.3%) 0.66
TG 42(20.2%) 76(13.0%)  
CT 4(1.9%) 4(0.7%)  
CG 34(16.4%) 122(21.0%)  
  1. aTwo SNP diplotypes span the genomic region of exon 9 (rs2273346 and rs12711521).