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Table 4 Diagnostic accuracy of serum PCT for the diagnosis of nosocomial infection.

From: Serum procalcitonin for the early recognition of nosocomial infection in the critically ill patients: a preliminary report

PCT value AUROCC
(95% CI)
cut-off value Sensitivity
(%)
Specificity
(%)
Positive
predictive
value (%)
Negative
predictive
value (%)
LR+ LR-
PCT D0 0.80
(0.68–091)
0.44 65.2 83.0 83.0 65.2 3.83 0.42
ΔPCTD-1, D0 * 0.89
(0.79–0.98)
+0.26 75.8 100 100 68.0 NA 0.24
ΔPCTD-2, D0 ** 0.89
(0.75–0.96)
+0.20 67.9 100 100 64.0 NA 0.32
ΔPCTD-3, D0 *** 0.84
(0.71–0.93)
+0.21 61.8 100 100 56.7 NA 0.38
  1. PCT: procalcitonin; AUROCC: Area Under the Receiver Operating Characteristic Curve; CI: Confidence Interval; LR: Likelihood Ratio; NA: not applicable
  2. ΔPCTD-1, D0 = PCT D0 – PCT D-1; D0: day when infection is clinically suspected.
  3. *available in 45 out of the 70 included patients; **available in 44 out of the 70 included patients; ***available in 51 out of the 70 included patients.