Characteristics
|
Initial therapy
|
P-value
|
---|
|
Effective (n = 8)
|
Ineffective (n = 18)
| |
---|
Age (mean in year, SD)
|
62.1 ± 9.3
|
58.3 ± 10.4
|
0.363
|
Male (n, %)
|
4 (50%)
|
15 (83%)
|
0.149
|
Escherichia coli (n, %)
|
5 (63%)
|
12 (67%)
|
1.000
|
Child-Pugh score (mean, SD)
|
10.4 ± 1.6
|
11.1 ± 1.6
|
0.330
|
APACHE II score (mean, SD)
|
15.6 ± 3.8
|
15.6 ± 3.7
|
0.993
|
Outcomes
| | | |
Initial response†
| | | |
Complete response (n, %)
|
1 (13%)
|
1 (6%)
|
0.529
|
Treatment failure (n, %)
|
2 (25%)
|
13 (72%)
|
0.038
|
7-day mortality (n, %)
|
1 (13%)
|
8 (44%)
|
0.190
|
30-day mortality (n, %)
|
1 (13%)
|
11 (61%)
|
0.036
|
- SD – standard deviation
- APACHE II – Acute Physiologic and Chronic Health Evaluation II
-
† Initial response was assessed 72 hours after the initiation of empirical treatment