Risk factors that were present | First phase of study (2000/3) | Second phase of study (2006) | ||||
---|---|---|---|---|---|---|
HFMD-CNS (N = 102) | HFMD-Non-CNS (N = 83) | Mild HFMD (N = 540) | HFMD-CNS (N = 250) | HFMD-Non-CNS (N = 186) | Mild HFMD (N = 294) | |
No. of patients with none of the 3 risk factor | 2 | 9 | 352 | 11 | 52 | 208 |
Peak temperature ≥ 38.5°C only | 1 | 8 | 7 | 29 | 32 | 34 |
History of lethargy only | 5 | 15 | 27 | 16 | 11 | 17 |
Total duration of fever ≥ 3 only | 9 | 15 | 122 | 32 | 35 | 30 |
No. of patients with 1 risk factor | 15 | 38 | 156 | 77 | 78 | 81 |
Peak temperature ≥ 38.5°C plus history of lethargy | 2 | 3 | 1 | 11 | 7 | 2 |
Peak temperature ≥ 38.5°C plus total duration of fever ≥ 3 days | 25 | 15 | 8 | 76 | 31 | 3 |
Total duration of fever ≥ 3 days plus history of lethargy | 26 | 12 | 19 | 21 | 5 | 0 |
No. of patients with 2 risk factors | 53 | 30 | 28 | 108 | 43 | 5 |
No. of patients with 3 risk factors (Peak temperature ≥ 38.5°C plus total duration of fever ≥ 3 days plus history of lethargy) | 32 | 6 | 4 | 54 | 13 | 0 |