Identification and validation of clinical predictors for the risk of neurological involvement in children with hand, foot, and mouth disease in Sarawak

Table 1 Risk factors that were significantly associated with CSF pleocytosis in children with HFMD in the first phase of the study (2000 to 2003).

Risk factors	p value	Odds ratio	95% CI
Total duration of fever ≥ 3 days	< 0.0001	6.52	2.83 – 14.99
Peak temperature ≥ 38.5°C	0.0192	2.27	1.14 – 4.51
History of lethargy	0.001	3.18	1.60 – 6.35

Note: The Hosmer-Lemeshow statistics indicated a non-significance of lack of fit (χ² = 2.163, p = 0.904).
CSF: Cerebrospinal fluid
HFMD: Hand, foot, and mouth disease

ISSN: 1471-2334