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Table 1 Sensitivities, specificities and likelihood ratios of AFB smear plus Culture and AFB smear plus PCR dot-Blot

From: Cost-effectiveness analysis of PCR for the rapid diagnosis of pulmonary tuberculosis

Laboratory Results and Performance of methodsa

Total number of suspects

N = 277

  

TB

N = 128

Not-TB

N = 149

Performance of AFB smear plus Culture

Positive

111

1

 

Negative

17

148

  

SE

SP

LR+

LR-

  

87%

99%

89

0.13

Performance of AFB smear plus PCR dot-blot

Positive

109

22

 

Negative

19

127

  

SE

SP

LR+

LR-

  

85%

85%

5.31

0.18

  1. SE: Sensitivity, SP: Specificity, LR+: Positive Likelihood Ratio, LR-: Negative Likelihood Ratio. aThe performance of tests was calculated using specific formulae utilized by parallel tests: sensitivity (SE) of AFB smear with culture: (SEzn + SEculture) - (SEzn × SEculture), specificity (SP) of AFB smear with culture: SPzn.X SPculture, predictive values (PV) and likelihood ratio (LR), according to literature [32].