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Table 1 Demographic and clinical data of the patient population

From: Diagnostic and prognostic value of procalcitonin among febrile critically ill patients with prolonged ICU stay

 

Proven infection

(n = 27)

Unproven infection

(n = 23)

P

Age, years

70 ± 12.1

56 ± 22.1

0.03

Gender (male)

20 (74%)

18 (78%)

NS

ICU stay duration until study enrollment

25 ± 12

29 ± 14

NS

APACHE II score on study enrollment

20.5 ± 4.4

15.3 ± 4.1

<0.001

SOFA score on day 1 (Day of fever)

10.1 ± 3

6.2 ± 2.4

0.004

Δ SOFA score

2.7 ± 1.9

0.6 ± 1

<0.001

28-day mortality

15/27 (56%)

7/23 (30%)

NS

Day 1 (Day of fever) status

   

   SIRS

1 (4%)

6 (26%)

NS

   SIRS+New organ failure (besides circulation)

13 (48%)

14 (61%)

NS

   Shock

13 (48%)

3 (13%)

0.07

Admission category

   

   Respiratory

7 (26%)

6 (26%)

NS

   Cardiovascular

6 (22%)

3 (13%)

NS

   Neurological

9 (33%)

10 (43%)

NS

   Trauma/Surgical

5 (19%)

2 (9%)

NS

Co-morbidities

   

   Malignancy

2 (7%)

2 (9%)

NS

   CRRT

8 (30%)

5 (22%)

NS

   Steroids

4 (15%)

3 (13%)

NS

Previous septic episodes

  

NS

MDR pathogens in the last tracheal aspirate

27/27 (100%)

21/23 (91%)

NS

MDR pathogens in the last anal swab

27/27 (100%)

20/23 (87%)

NS

Proven infection

17/27(63%)

13/23(56%)

NS

   Ventilator-associated pneumonia

16 (60%)

0

 

   Bloodstream infection

8 (30%)

0

 

   Abdominal infection

3 (10%)

0

 
  1. ICU: Intensive Care Unit, APACHE: Acute Physiology and Chronic Health Evaluation, SOFA: System Organ Failure Assessment, ΔSOFA: difference between Day 1 (fever) and Day 0 in SOFA score, SIRS: Systemic Inflammatory Response Syndrome, CRRT: Continuous Renal Replacement Therapy, MDR: Multi-Drug Resistant.