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Table 2 Characteristics of study subjects.

From: Lymphocyte proliferation to mycobacterial antigens is detectable across a spectrum of HIV-associated tuberculosis

 

Subjects without TB

(n = 1206)

Subjects with latent TB

(n = 635)

Subjects with active TB

(n = 13)

P-value by ANOVA

Age, mean

33.0

33.5

34.1

0.5102

Male, % (n)

247 (20.5%)

193 (30.4%)

3 (23.1%)

< 0.0001

CD4 cells/mm3, mean

455

502

376

0.0001

HIV viral load, copies/mL, mean

37,286

28,365

87,293

0.0063

Previous TB, % (n)

98 (8.1%)

61 (9.6%)

2 (15.4%)

0.3865

On antiretrovirals, % (n)

44 (3.6%)

13 (2.0%)

0 (0%)

0.1366

TST, mm, mean

0.2

15.5

15.0

< 0.0001

TST ≥ 5 mm, % (n)

0 (0%)

635 (100%)

11 (84.6%)

< 0.0001

MAS, mm, mean

0.3

9.6

10.1

< 0.0001

MAS ≥ 5 mm, % (n)

835 (69.2%)

582 (91.7%)

10 (76.9%)

< 0.0001

  1. ANOVA = analysis of variance; HIV = human immunodeficiency virus; MAS = Mycobacterium avium sensitin skin test; TB = tuberculosis; TST = tuberculin skin test