| NAR group (n = 22) | AI group (n = 19) | Pvalue |
---|---|---|---|
Age (yrs) | 67 (50-71) | 68 (55-74) | 0.574 |
Male (n) | 14 | 16 | 0.233 |
APACHE II | 27 (21-29) | 27 (19-32) | 0.582 |
SOFA score | 9 (5-11) | 8 (6-11) | 0.793 |
JAAM DIC score | 3.0 (1.75-5.0) | 3.0 (2.0-5.0) | 0.433 |
Severe sepsis/septic shock (n) | 19/3 | 7/12 | 0.001 |
Survivors/non-survivors (n) | 16/6 | 13/6 | 0.763 |
Albumin (g/dL) | 2.1 (1.7-2.5) | 2.0 (1.6-2.2) | 0.636 |
Prothrombin time ratio | 1.2 (1.1-1.3) | 1.3 (1.2-1.5) | 0.025 |
MIF (ng/mL) | 16.6 (14.5-20.1) | 23.8 (17.6-44.5) | 0.010 |
Baseline cortisol (μg/dL) | 18.9 (14.3-25.3) | 27.6 (17.6-46.8) | 0.028 |
Baseline cortisol/albumin ratio | 10.3 (8.6-13.0) | 15.1 (9.4-20.0) | 0.053 |
Delta max cortisol (μg/dL) | 15.5 (9.9-19.6) | 4.6 (1.4-7.3) | < 0.001 |
Delta max cortisol/albumin ratio | 7.5 (6.0-8.5) | 2.3 (0.8-3.3) | < 0.001 |
Site of infection (n) | Â | Â | Â |
Respiratory tract | 11 | 7 | Â |
Skin and soft tissue | 3 | 5 | Â |
Gastrointestinal tract | 2 | 3 | Â |
Urinary tract | 1 | 2 | Â |
Peritonitis | 2 | 1 | Â |
Meningitis | 1 | 0 | Â |
Infectious endocarditis | 1 | 0 | Â |
Unknown | 0 | 1 | Â |