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Table 4 Characteristics of patients with indeterminate and determinate QFT-IT results

From: Performance of the tuberculin skin test and interferon-γ release assay for detection of tuberculosis infection in immunocompromised patients in a BCG-vaccinated population

Characteristic Indeterminate n= 34 Determinate n= 177 p
Age, median (range) 61 (20-98) 54 (19-85) 0.52
Male/female 13/21 84/93 0.32
BMI, (median, IQR) 21.6 (20.8-25.4) 21.5 (19.2-24.4) 0.28
Recent TB contact    1.0*
   Negative 25 (73.5) 156 (88.1)  
   Positive 0 (0) 2 (1.1)  
   Unknown 9 (26.5) 19 (10.7)  
Presence of TB scar on chest X-ray 0 (0) 7 (4.0) 0.24
History of smoking 4 (12) 30 (17) 0.44
Hypertension 12 (35) 37 (21) 0.07
Positive results of TST 1 (3) 49 (28) 0.002
Immunosuppressive condition 25 (74) 92 (52) 0.02
   Diabetes 3 20  
   Solid cancer treated with anticancer chemotherapy 2 26  
   Haematologic malignant disease 2 5  
   Transplantation 4 7  
   ESRD on renal replacement therapy 1 5  
   Liver cirrhosis, Child-Pough class C 0 1  
   HIV infection 0 1  
   Treated with immunosuppressive drugs 13 27  
Laboratory findings, (median, IQR)    
   WBC (103/uL) 10 695 (4840-16275) 7160 (5510-9660) 0.04
   Haemoglobin (g/dL) 9.9 (8.9-10.9) 11.5 (9.8-13.1) < 0.001
   Platelets (103/uL) 317 (214-399) 267 (196-376) 0.43
   Lymphocytes (103/uL) 780 (435-1582) 1500 (1005-1925) < 0.001
   Total protein (g/dL) 6.45 (5.3-6.8) 6.9 (6.2-7.4) < 0.001
   Albumin (g/dL) 3.0 (2.7-3.2) 3.8 (3.1-4.2) < 0.001
   Cholesterol (mg/dL) 138 (109-182) 156 (125-184) 0.12
  1. Data are presented as numbers (percentages) unless otherwise indicated.
  2. MI, body mass index; ESRD, end-stage renal disease; IQR, interquartile range; QFT-IT, QuantiFERON-TB Gold In-Tube; TB, tuberculosis; TST, tuberculin skin test; WBC, white blood cells.
  3. *p 1.00 for the difference in history of recent TB contact, except where unknown.