Skip to main content

Table 4 Characteristics of patients with indeterminate and determinate QFT-IT results

From: Performance of the tuberculin skin test and interferon-γ release assay for detection of tuberculosis infection in immunocompromised patients in a BCG-vaccinated population

Characteristic

Indeterminate

n= 34

Determinate

n= 177

p

Age, median (range)

61 (20-98)

54 (19-85)

0.52

Male/female

13/21

84/93

0.32

BMI, (median, IQR)

21.6 (20.8-25.4)

21.5 (19.2-24.4)

0.28

Recent TB contact

  

1.0*

   Negative

25 (73.5)

156 (88.1)

 

   Positive

0 (0)

2 (1.1)

 

   Unknown

9 (26.5)

19 (10.7)

 

Presence of TB scar on chest X-ray

0 (0)

7 (4.0)

0.24

History of smoking

4 (12)

30 (17)

0.44

Hypertension

12 (35)

37 (21)

0.07

Positive results of TST

1 (3)

49 (28)

0.002

Immunosuppressive condition

25 (74)

92 (52)

0.02

   Diabetes

3

20

 

   Solid cancer treated with anticancer chemotherapy

2

26

 

   Haematologic malignant disease

2

5

 

   Transplantation

4

7

 

   ESRD on renal replacement therapy

1

5

 

   Liver cirrhosis, Child-Pough class C

0

1

 

   HIV infection

0

1

 

   Treated with immunosuppressive drugs

13

27

 

Laboratory findings, (median, IQR)

   

   WBC (103/uL)

10 695 (4840-16275)

7160 (5510-9660)

0.04

   Haemoglobin (g/dL)

9.9 (8.9-10.9)

11.5 (9.8-13.1)

< 0.001

   Platelets (103/uL)

317 (214-399)

267 (196-376)

0.43

   Lymphocytes (103/uL)

780 (435-1582)

1500 (1005-1925)

< 0.001

   Total protein (g/dL)

6.45 (5.3-6.8)

6.9 (6.2-7.4)

< 0.001

   Albumin (g/dL)

3.0 (2.7-3.2)

3.8 (3.1-4.2)

< 0.001

   Cholesterol (mg/dL)

138 (109-182)

156 (125-184)

0.12

  1. Data are presented as numbers (percentages) unless otherwise indicated.
  2. MI, body mass index; ESRD, end-stage renal disease; IQR, interquartile range; QFT-IT, QuantiFERON-TB Gold In-Tube; TB, tuberculosis; TST, tuberculin skin test; WBC, white blood cells.
  3. *p 1.00 for the difference in history of recent TB contact, except where unknown.