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Table 3 Clinical results of Shigella infections between 1995 and 2008.

From: A changing picture of shigellosis in southern Vietnam: shifting species dominance, antimicrobial susceptibility and clinical presentation

 

A (1995 - 1996)

B (2000 - 2002)

C (2007 - 2008)

Combined

pvaluea

Pateints

n = 63

n = 113

n = 103

n = 279

 

Age (months)d

23 (17 - 48)

21 (14 - 29)

30 (19 - 42)

24 (16 - 36)

< 0.001

Weight (kg)

10 (9 - 13)

10 (9 - 12)

11.5 (10 - 15)

10.5 (9 - 13)

0.004

Male sex (%)

31 (49)

50 (44)

61 (59)

184 (59%)

0.085

Patient history

     

Days

2 (1 - 7)

2 (1 - 9)

1 (1 - 4)

2 (1 - 9)

< 0.001

Fever (%)

62 (98)

104 (92)

100 (97)

266 (95)

0.09

Abdominal pain (%)

33 (52)

41 (36)

79 (76)

153 (54)

< 0.001

Vomitting (%)

24 (38)

64 (56)

51 (49)

139 (50)

0.062

Watery diarrhea (%)

28 (44)

67 (59)

74 (71)

169 (60)

0.002

Bloody/mucoid diarrhea (%)

63 (100)

60 (53)

98 (95)

221 (79)

< 0.001

Diahorreal episodes per day

NA

8 (5-10)

8 (5-10)

8 (5-10)

0.595

Convulsions (%)

4 (6)

7 (6)

20 (19.4)

31 (11)

< 0.001

Known pretreatment (%)

3 (5)

8 (7)

4 (4)

14 (5)

0.543

Clinical details

     

Serotype sonnei (%)

21/63 (33)

55/113 (49)

71/103 (69)

153/279 (55)

< 0.001

White cell count (× 103/mm3)

10 (8.3 - 15)

10.1 (7.7 - 12.8)

13.1 (10.1 - 17.3)

11.3 (8.7 - 15.4)

< 0.001

Red cells in stoolb

NA

1

1

1

0.715

White cells in stoolb

NA

3

3

3

0.02

Mucoid duration (hrs)

31.5 (24 - 53.5)

36 (24 - 54)

28 (18 - 48)

30 (19.5 - 48)

0.113

Diarrhea duration (hrs)

48.5 (29.25 - 87)

48 (24 - 72)

48 (30 - 72)

48 (26.75 - 72)

0.402

Duration of illness

     

Hospital stay (days)

3 (1 - 12)

4 (1 -15)

5 (2 - 14)

4 (1 -15)

< 0.001

Disease duration (days)c

4 (2 - 15)

6 (3 - 18)

6 (3 - 15)

6 (2 - 18)

< 0.001

  1. a p Values calculated using either Chi-square test or the Kruskal-Wallis test
  2. b Cells in Stools assessed as described in methods
  3. c Disease duration calculated by addition of history of disease and stay in hospital
  4. d Interquartile range values in brackets unless stated