Figure 3
From: Differential protein profiling as a potential multi-marker approach for TSE diagnosis
Panel of biomarkers. (A) data from the ProteinChip® Reader is visualized in spectral format as clusters of differentially expressed protein peaks at 7063 (cluster X21), 7847(X26), 8811 (X31), 10101 (X34), 10300 (X35), 12449 (X43) m/z. Each peak within a cluster represents an individual brain sample i.e. 12 scrapie infected (red) and 12 uninfected (green) animals. Corresponding box plots for each marker displays the separation of markers based on peak height intensity, scrapie infected (red) uninfected (green). (B) cluster analysis shows separation of groups, scrapie infected (ME7) and uninfected (NB) samples. (C) pairwise plots of the above six highly significant proteins one protein against the other (red indicates scrapie infected green indicates control).